ID E9HIS8_DAPPU Unreviewed; 552 AA.
AC E9HIS8;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE RecName: Full=Nostrin {ECO:0008006|Google:ProtNLM};
GN ORFNames=DAPPUDRAFT_301481 {ECO:0000313|EMBL:EFX68361.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX68361.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX68361.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL732657; EFX68361.1; -; Genomic_DNA.
DR AlphaFoldDB; E9HIS8; -.
DR EnsemblMetazoa; EFX68361; EFX68361; DAPPUDRAFT_301481.
DR KEGG; dpx:DAPPUDRAFT_301481; -.
DR eggNOG; KOG4429; Eukaryota.
DR HOGENOM; CLU_027170_0_0_1; -.
DR InParanoid; E9HIS8; -.
DR OMA; YSAWCHV; -.
DR PhylomeDB; E9HIS8; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR CDD; cd11823; SH3_Nostrin; 1.
DR Gene3D; 6.10.140.470; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR035656; Nostrin_SH3.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23065:SF62; NOSTRIN, ISOFORM H; 1.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000000305};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 12..273
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 495..552
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 430..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 436..490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 552 AA; 62266 MW; D20B0885A467A3B4 CRC64;
MNVFDNKTII NYFFFSLFQS QNGFEELRLH VKEGGDLCKE LSAILQERSE LEASYAKGLA
KLASKLLKTT GELQGPHGTV TAGWSAVAMK MESEAELHKS LSVALSEELV KPLKVAVESQ
HRVRKAVESG VDKTGRMLAE WRSAQAKAKK HCYMSARENE KMQDQVFINK PRVLTDKETA
KLEAKCKKTQ EAVRKAEGEY YTCCTKAERS RLEWESTTQR GGRCFHALEQ ERLEQLKDLL
SKYYVCFRDY CPKMCQAVDR LVEPVSTCNV DIDLQSVSSL RDSAPTFAEQ LLPDFYAEHM
SNVMNRERRK ESLERCLHWV RSDLERESRG RRGVENLAKA LQESPHFGGE ESQLEVHEKL
LHLRSMLAFL EMTRVKLHNS AHELEPIRYR KVDHPLFKYL SVHKDKQGMM QSVLKLPHWI
DNEDIEIELN EDGRGTGDGN SGQVDSDFDE FSSQGSDGEV SSHSVIQRNG GGVSSNAGST
SSSSTTTDNT TVIVPSVGKC RALYSYAANM YDELSIQPGD VINIHDKQAD GWWLGELSGT
VGIFPATYVE EV
//
