ID E9I100_DAPPU Unreviewed; 902 AA.
AC E9I100;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE RecName: Full=Peptidase A2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DAPPUDRAFT_120328 {ECO:0000313|EMBL:EFX62330.1};
OS Daphnia pulex (Water flea).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda;
OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia.
OX NCBI_TaxID=6669 {ECO:0000313|EMBL:EFX62330.1, ECO:0000313|Proteomes:UP000000305};
RN [1] {ECO:0000313|EMBL:EFX62330.1, ECO:0000313|Proteomes:UP000000305}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21292972; DOI=10.1126/science.1197761;
RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A.,
RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., Bauer D.J.,
RA Caceres C.E., Carmel L., Casola C., Choi J.H., Detter J.C., Dong Q.,
RA Dusheyko S., Eads B.D., Frohlich T., Geiler-Samerotte K.A., Gerlach D.,
RA Hatcher P., Jogdeo S., Krijgsveld J., Kriventseva E.V., Kultz D.,
RA Laforsch C., Lindquist E., Lopez J., Manak J.R., Muller J., Pangilinan J.,
RA Patwardhan R.P., Pitluck S., Pritham E.J., Rechtsteiner A., Rho M.,
RA Rogozin I.B., Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y.,
RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., Tu H.,
RA Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., Shaw J.R.,
RA Andrews J., Crease T.J., Tang H., Lucas S.M., Robertson H.M., Bork P.,
RA Koonin E.V., Zdobnov E.M., Grigoriev I.V., Lynch M., Boore J.L.;
RT "The ecoresponsive genome of Daphnia pulex.";
RL Science 331:555-561(2011).
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DR EMBL; GL733664; EFX62330.1; -; Genomic_DNA.
DR AlphaFoldDB; E9I100; -.
DR EnsemblMetazoa; EFX62330; EFX62330; DAPPUDRAFT_120328.
DR KEGG; dpx:DAPPUDRAFT_120328; -.
DR HOGENOM; CLU_321504_0_0_1; -.
DR InParanoid; E9I100; -.
DR Proteomes; UP000000305; Unassembled WGS sequence.
DR GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProt.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR CDD; cd00303; retropepsin_like; 1.
DR Gene3D; 2.40.70.10; Acid Proteases; 1.
DR InterPro; IPR001969; Aspartic_peptidase_AS.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR PANTHER; PTHR38128; GAMETOCYTOGENESIS-IMPLICATED PROTEIN; 1.
DR PANTHER; PTHR38128:SF2; OLIGOMERIC GOLGI COMPLEX SUBUNIT 4, PUTATIVE-RELATED; 1.
DR SUPFAM; SSF50630; Acid proteases; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS00141; ASP_PROTEASE; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000305}.
FT REGION 279..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 781..902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 781..810
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 811..849
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 852..876
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFX62330.1"
SQ SEQUENCE 902 AA; 103167 MW; CB6A6973D77B94B9 CRC64;
MGNQVDEQIL RLYLDVKEPS NKILPDLTSQ LPFLNLALHT LKERRNDFQS GERKIWKQLR
ELMRDIKWTI DDPKPIDLTQ AFYTLQCLTH LVESQATPPI PIISKKSKTI LKETKEIFLT
YTRRILTFQL GQYLSLRTLE EYVPNPPAEF LGFVKREDIA NRDESGDYHE FLLNQIEFMF
DFLHESFDTF QKIFLENTQT LIQFLKKLHK IQSIHNFQPE LIRLQYRLNN FPRINWTFDR
EEVDNNKTLL AKTKRDLQIV LDFLQAPPPP HQSQIVRQAA TPCHAHSKTR RAQRYRQPRR
HLPDDRAREG PPTTAAGKPV NINCGFGSVD REPHNKSRQI ARLTTQNNES TPRIPLTSFQ
IPFQALFDTG AARSIIHEKL FRKLPLQSRD TCSTLDFNLY DVHNKKLNTL GKVTLPIRYG
KSTLLQEFII TDGISEDCIL GWDAIRKHGF TIDGETSSIY LAKETLGQAK SRAPDISIIL
HKRRAICRRT AVVVEAKTTG SFPYVSPLAT FIFTPSEKLP KGIHIQQFIG RISASGKYEI
IIENQSSNDI FLPRAIQLGT IEVVCNVIGQ VTCKSTGEEN TIDDELDLTI IRDVDPQFQK
PVLQILTDFK KMFATKNSQL GSTDLIKHSI DIQGRGPIRQ RPYRHPRSHT AALQRQLSEL
KKAGIIRVAE ESGKARERQR AQYNKRANEN EYKVGDKVLL DIRVVKTGDS KKFTSKYKGP
YRIIKVYANK TVDIADSSYV TQRVHVNRVK PLFETMLWRQ EPCPAFESTF DVGNWYRATT
ETDTQTAKDP NGKAQRAKNN SSATCATSGD KDNESDWETC SDCSTDSDNE KNKIIRGKED
VREDVTETLQ ENTNEEETIQ NAEIGVEPST SASPNKVKKK VGRPKKSAHP VNPSTSPAQT
EQ
//
