ID   E9KMC6_OCELE            Unreviewed;       397 AA.
AC   E9KMC6;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   03-MAY-2023, entry version 41.
DE   SubName: Full=TLR2B {ECO:0000313|EMBL:ADV75085.1};
DE   Flags: Fragment;
GN   Name=TLR2B {ECO:0000313|EMBL:ADV75085.1};
OS   Oceanodroma leucorhoa (Leach's storm-petrel) (Hydrobates leucorhous).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Procellariiformes; Hydrobatidae;
OC   Oceanodroma.
OX   NCBI_TaxID=52124 {ECO:0000313|EMBL:ADV75085.1};
RN   [1] {ECO:0000313|EMBL:ADV75085.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=21239391; DOI=10.1093/molbev/msq351;
RA   Alcaide M., Edwards S.V.;
RT   "Molecular evolution of the toll-like receptor multigene family in birds.";
RL   Mol. Biol. Evol. 28:1703-1715(2011).
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DR   EMBL; GU904959; ADV75085.1; -; Genomic_DNA.
DR   AlphaFoldDB; E9KMC6; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR000483; Cys-rich_flank_reg_C.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR017241; Toll-like_receptor.
DR   PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR   PANTHER; PTHR24365:SF17; TOLL-LIKE RECEPTOR 2; 1.
DR   Pfam; PF13855; LRR_8; 2.
DR   SMART; SM00369; LRR_TYP; 4.
DR   SMART; SM00082; LRRCT; 1.
DR   SUPFAM; SSF52058; L domain-like; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS51450; LRR; 2.
PE   4: Predicted;
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Signal {ECO:0000256|ARBA:ARBA00022729};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        350..371
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          294..347
FT                   /note="LRRCT"
FT                   /evidence="ECO:0000259|SMART:SM00082"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ADV75085.1"
FT   NON_TER         397
FT                   /evidence="ECO:0000313|EMBL:ADV75085.1"
SQ   SEQUENCE   397 AA;  44782 MW;  BF89D60FA713DAF2 CRC64;
     AEMQLLRVMS SSFAKKLSFK QTLLTDATVP KIVSILEDMP QLVEVEMIDC RLLGTGQWQT
     HIKANQSRTF RVLTIEKISI EEFYLFTDLQ AVQDLLSLLT KVTVENTKVF LVPCRLSQKL
     LSLEYLDLSA NLLGDQSLEH SACQGGWPSL QTLNLSQNSL SDLEMTVKSL SHLRNLILLD
     ISQNNFGDIP DVCEWPQTLK YLNLSSTQIP KLTTCIPPTL EVLDVSANNL KEFGLQLPYL
     KELYLAKNQL KALPGAAPVP NLVAMSIRRN KLNGFSREEF ESFRKMELLD ASDNNFICSC
     EFLSFIHHEA GIAQVLVGWP DKYVCDSPLA VRGTQVGAVH LSLMECHRSL VVSSICVLLF
     LVILILVAVS YKYHAVWYLR MTWAWLQAKR KPKQAPP
//