ID E9LHE9_9LACO Unreviewed; 120 AA.
AC E9LHE9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-APR-2011, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=phenylalanine--tRNA ligase {ECO:0000256|ARBA:ARBA00012814};
DE EC=6.1.1.20 {ECO:0000256|ARBA:ARBA00012814};
DE Flags: Fragment;
GN Name=pheS {ECO:0000313|EMBL:ADW23123.1};
OS Lacticaseibacillus manihotivorans.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=88233 {ECO:0000313|EMBL:ADW23123.1};
RN [1] {ECO:0000313|EMBL:ADW23123.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=M7.1.16 {ECO:0000313|EMBL:ADW23123.1};
RX PubMed=21092306; DOI=10.1186/1471-2180-10-298;
RA Lucena B.T., Dos Santos B.M., Moreira J.L., Moreira A.P., Nunes A.C.,
RA Azevedo V., Miyoshi A., Thompson F.L., de Morais M.A.;
RT "Diversity of lactic acid bacteria of the bioethanol process.";
RL BMC Microbiol. 10:298-298(2010).
RN [2] {ECO:0000313|EMBL:ADW23123.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=M7.1.16 {ECO:0000313|EMBL:ADW23123.1};
RA de Lucena B.T.L., dos Santos B.M., Moreira J.L.S., Moreira A.P.B.,
RA Nunes A.C., Azevedo V.A., Thompson F.L., de Morais M.A.Jr.;
RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) +
CC L-phenylalanyl-tRNA(Phe); Xref=Rhea:RHEA:19413, Rhea:RHEA-COMP:9668,
CC Rhea:RHEA-COMP:9699, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:58095, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78531, ChEBI:CHEBI:456215; EC=6.1.1.20;
CC Evidence={ECO:0000256|ARBA:ARBA00000395};
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DR EMBL; HQ009765; ADW23123.1; -; Genomic_DNA.
DR AlphaFoldDB; E9LHE9; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004826; F:phenylalanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0016740; F:transferase activity; IEA:UniProt.
DR GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR GO; GO:0043039; P:tRNA aminoacylation; IEA:InterPro.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR002319; Phenylalanyl-tRNA_Synthase.
DR PANTHER; PTHR11538:SF41; PHENYLALANINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11538; PHENYLALANYL-TRNA SYNTHETASE; 1.
DR Pfam; PF01409; tRNA-synt_2d; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000313|EMBL:ADW23123.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Ligase {ECO:0000313|EMBL:ADW23123.1}.
FT DOMAIN 1..103
FT /note="Aminoacyl-transfer RNA synthetases class-II family
FT profile"
FT /evidence="ECO:0000259|PROSITE:PS50862"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADW23123.1"
FT NON_TER 120
FT /evidence="ECO:0000313|EMBL:ADW23123.1"
SQ SEQUENCE 120 AA; 13377 MW; A7C42846540368FB CRC64;
GNDLLMRSQT SPVQARTLEV HDFSKGPLKM ISPGRVYRRD TDDATHSHQF HQVEGLVIDK
HITMADLKGT LLAVAQHVFG KDRTIRLRPS YFPFTEPSVE VDVSCFRCGG KGCAICKYSG
//
