ID   E9NH80_PRIPA            Unreviewed;       465 AA.
AC   E9NH80;
DT   05-APR-2011, integrated into UniProtKB/TrEMBL.
DT   05-APR-2011, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Cellulase 2 {ECO:0000313|EMBL:ADV58333.1};
DE            EC=3.2.1.4 {ECO:0000313|EMBL:ADV58333.1};
DE   Flags: Fragment;
GN   Name=cel-2 {ECO:0000313|EMBL:ADV58333.1};
OS   Pristionchus pacificus (Parasitic nematode).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Diplogasteromorpha; Diplogasteroidea; Neodiplogasteridae;
OC   Pristionchus.
OX   NCBI_TaxID=54126 {ECO:0000313|EMBL:ADV58333.1};
RN   [1] {ECO:0000313|EMBL:ADV58333.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=RS5302 {ECO:0000313|EMBL:ADV58333.1};
RX   PubMed=21232122; DOI=10.1186/1471-2148-11-13;
RA   Mayer W.E., Schuster L.N., Bartelmes G., Dieterich C., Sommer R.J.;
RT   "Horizontal gene transfer of microbial cellulases into nematode genomes is
RT   associated with functional assimilation and gene turnover.";
RL   BMC Evol. Biol. 11:13-13(2011).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000256|ARBA:ARBA00005641, ECO:0000256|RuleBase:RU361153}.
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DR   EMBL; HQ632075; ADV58333.1; -; Genomic_DNA.
DR   AlphaFoldDB; E9NH80; -.
DR   HOGENOM; CLU_020735_1_0_1; -.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR019028; CBM_49.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR35923:SF2; CELLULASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR35923; MAJOR EXTRACELLULAR ENDOGLUCANASE; 1.
DR   Pfam; PF09478; CBM49; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361153};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361153}.
FT   DOMAIN          12..294
FT                   /note="Glycoside hydrolase family 5"
FT                   /evidence="ECO:0000259|Pfam:PF00150"
FT   DOMAIN          403..455
FT                   /note="Carbohydrate binding"
FT                   /evidence="ECO:0000259|Pfam:PF09478"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ADV58333.1"
FT   NON_TER         465
FT                   /evidence="ECO:0000313|EMBL:ADV58333.1"
SQ   SEQUENCE   465 AA;  51212 MW;  567966D69905A4D6 CRC64;
     ILVNGQPLVL KGINYFGFET ETYTPHGIWS YDLNVYLDFI KNNNFNAIRV PFSLEMVKNN
     PSNLNINCAT NPGLCGKSAL QLLDVFIDRA AERGFLIMLD NHRITPGGGI SELWYNNEYP
     ESQKFTKTHC RWNVFEIDLK NEPHDSASWG NSNAATDWNK AAERIINSLS SFLGLFFVEG
     IEWGNRLENV AQFPINTGNP SLNNRVVYSP HCYGPSVYDR PEFNTPDFPN NLDGMYMVKY
     GFVVNQTGQP VVVGEWGGRA EVGSKDMTWN QWYIEWLRSK CITNNFYWCL NPNSADTGGL
     LEDDWLTPIP RKINLTNRAQ PNPTKFQAQN GQICITAGAF PEAHCQVGVK VTDGPGTTTT
     TVNAGPTTIT TSAPIAPSTA VAQAPSTTTV PSSGGGGVTL STENGSAVKQ YTLRISNGSP
     STVCSVHIKL NASIKDKWNL DEVSSDLYRT PSWMTIAPDA VADQA
//