ID E9PQT9_HUMAN Unreviewed; 93 AA.
AC E9PQT9;
DT 05-APR-2011, integrated into UniProtKB/TrEMBL.
DT 05-OCT-2016, sequence version 8.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Discs large MAGUK scaffold protein 2 {ECO:0000313|Ensembl:ENSP00000434346.1};
DE Flags: Fragment;
GN Name=DLG2 {ECO:0000313|Ensembl:ENSP00000434346.1};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000434346.1, ECO:0000313|Proteomes:UP000005640};
RN [1] {ECO:0000313|Ensembl:ENSP00000434346.1, ECO:0000313|Proteomes:UP000005640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16554811; DOI=10.1038/nature04632;
RA Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT "Human chromosome 11 DNA sequence and analysis including novel gene
RT identification.";
RL Nature 440:497-500(2006).
RN [2] {ECO:0000313|Ensembl:ENSP00000434346.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AP000773; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AP003026; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KC877445; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KC877447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KC877450; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; KF455429; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; E9PQT9; -.
DR SMR; E9PQT9; -.
DR MassIVE; E9PQT9; -.
DR PeptideAtlas; E9PQT9; -.
DR ProteomicsDB; 23117; -.
DR Antibodypedia; 8247; 429 antibodies from 35 providers.
DR Ensembl; ENST00000529399.1; ENSP00000434346.1; ENSG00000150672.19.
DR UCSC; uc058gce.1; human.
DR HGNC; HGNC:2901; DLG2.
DR VEuPathDB; HostDB:ENSG00000150672; -.
DR GeneTree; ENSGT00940000155156; -.
DR HOGENOM; CLU_151377_0_0_1; -.
DR OMA; XYARFEA; -.
DR ChiTaRS; DLG2; human.
DR Proteomes; UP000005640; Chromosome 11.
DR Bgee; ENSG00000150672; Expressed in cortical plate and 135 other cell types or tissues.
DR ExpressionAtlas; E9PQT9; baseline and differential.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR23122:SF72; DISKS LARGE 1 TUMOR SUPPRESSOR PROTEIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR23122; MEMBRANE-ASSOCIATED GUANYLATE KINASE MAGUK; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:E9PQT9,
KW ECO:0007829|MaxQB:E9PQT9};
KW Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 18..88
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT NON_TER 93
FT /evidence="ECO:0000313|Ensembl:ENSP00000434346.1"
SQ SEQUENCE 93 AA; 10740 MW; 78DABEB7555ADBA0 CRC64;
MMNHSMSSGS GSLRTNQKRS LYVRAMFDYD KSKDSGLPSQ GLSFKYGDIL HVINASDDEW
WQARRVMLEG DSEEMGVIPS KRRVERKERA RLK
//
