ID E9SD91_RUMAL Unreviewed; 878 AA.
AC E9SD91;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=PASTA domain protein {ECO:0000313|EMBL:EGC02754.1};
GN ORFNames=CUS_4404 {ECO:0000313|EMBL:EGC02754.1};
OS Ruminococcus albus 8.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Ruminococcus.
OX NCBI_TaxID=246199 {ECO:0000313|EMBL:EGC02754.1, ECO:0000313|Proteomes:UP000004259};
RN [1] {ECO:0000313|EMBL:EGC02754.1, ECO:0000313|Proteomes:UP000004259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=8 {ECO:0000313|EMBL:EGC02754.1,
RC ECO:0000313|Proteomes:UP000004259};
RA Nelson K.E., Sutton G., Torralba M., Durkin S., Harkins D., Montgomery R.,
RA Ziemer C., Klaassens E., Ocuiv P., Morrison M.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC02754.1}.
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DR EMBL; ADKM02000087; EGC02754.1; -; Genomic_DNA.
DR RefSeq; WP_002850287.1; NZ_ADKM02000087.1.
DR AlphaFoldDB; E9SD91; -.
DR STRING; 246199.CUS_4404; -.
DR eggNOG; COG0515; Bacteria.
DR eggNOG; COG2815; Bacteria.
DR OrthoDB; 9788659at2; -.
DR Proteomes; UP000004259; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR GO; GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
DR GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR CDD; cd06577; PASTA_pknB; 6.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 3.30.10.20; -; 6.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR045269; Atg1-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR005543; PASTA_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008266; Tyr_kinase_AS.
DR InterPro; IPR020635; Tyr_kinase_cat_dom.
DR PANTHER; PTHR24348:SF22; NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE; 1.
DR PANTHER; PTHR24348; SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED; 1.
DR Pfam; PF03793; PASTA; 6.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00740; PASTA; 6.
DR SMART; SM00219; TyrKc; 1.
DR SUPFAM; SSF54184; Penicillin-binding protein 2x (pbp-2x), c-terminal domain; 2.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51178; PASTA; 6.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00109; PROTEIN_KINASE_TYR; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000004259}.
FT DOMAIN 45..322
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 381..448
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 452..515
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 525..591
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 592..658
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 659..725
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT DOMAIN 726..792
FT /note="PASTA"
FT /evidence="ECO:0000259|PROSITE:PS51178"
FT REGION 790..851
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 790..819
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 834..851
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 74
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 878 AA; 97139 MW; 33DF3B17282E2E79 CRC64;
MKYCFGCMER YEDTLNTCPF CGYAEGTVSD NALHLRPGTI LQERYIVGKV IGYGGFGVTY
IGWDAVLETK IAIKEYLPSD FATRVLGHTQ LTVFSDNKNK QFNDGMKKFI NEAKKLAKFH
STPGIVKIFD SFEANNTAYI VMELLQGETL AEKLKREKKI PEDDAIEMIT PIIESLKVVH
SDGIIHRDIA PDNIFVTNSG EVKLIDFGAA RYATTSHSRS LTVIIKPGYS PEEQYRSKGD
QGAHTDVYAV AATLYKMITG VTPPDALERR AFFENKQKDI LEPITKYDKD ISDNHETAIL
NALSVRIEDR TPDMQTFLDE LNSEKPVTRR VGKIKKLDRL KWPLWAKIAI PSFAAAVAVF
STLLMTGVIS FDAGLKTKVE IPEGQTRVPS VISKEYNEGA DKLKASDLLV EISGLQPSDI
PADLILYQDI EAGTVVEVNT LVSVLVSSEL IKQPVPNVQG TEYEDAKEQL EGLGFKVKVK
KEYSDVIAEN CIISQSVPPE KEMPENSEVT LTISIGRDPS KEFHDKQLEV PDFSGMTFEE
AYAKASSLGM LIKVTDYRYS KEVEKNRIIE SDPAAGELIM NRMSVELVIS LGYAKVSVPK
LELMEEAQAV SQLKSRGLKA NIRYEYSDRI KEGLVISQDP KEKTEIEPES TVNLVVSKGT
EASDMPDVTG LRRDNAEEIL KQNGLVVTTS YKTDDSKTID TVLSQDPAKG EKVHRGDKVE
IVICTHETTV TLTDLTGLTR ANAEKQLKNK GLKVNVIEVE SSSANAGKVI SQLPASGTKL
KKNETVTINI GKHTSTQDTG NVQGGNTGET QSPRDTTMQT AKKTTKETER QTTKQTTRST
TKATEKQTSS KVYIVEFDEN YSSAPVSAYE YHAGDTIS
//
