ID E9SDS5_RUMAL Unreviewed; 912 AA.
AC E9SDS5;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 28-MAR-2018, entry version 30.
DE RecName: Full=Endoglucanase {ECO:0000256|RuleBase:RU361166};
DE EC=3.2.1.4 {ECO:0000256|RuleBase:RU361166};
GN ORFNames=CUS_7090 {ECO:0000313|EMBL:EGC02640.1};
OS Ruminococcus albus 8.
OC Bacteria; Firmicutes; Clostridia; Clostridiales; Ruminococcaceae;
OC Ruminococcus.
OX NCBI_TaxID=246199 {ECO:0000313|EMBL:EGC02640.1, ECO:0000313|Proteomes:UP000004259};
RN [1] {ECO:0000313|EMBL:EGC02640.1, ECO:0000313|Proteomes:UP000004259}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=8 {ECO:0000313|EMBL:EGC02640.1,
RC ECO:0000313|Proteomes:UP000004259};
RA Nelson K.E., Sutton G., Torralba M., Durkin S., Harkins D.,
RA Montgomery R., Ziemer C., Klaassens E., Ocuiv P., Morrison M.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY: Endohydrolysis of (1->4)-beta-D-glucosidic
CC linkages in cellulose, lichenin and cereal beta-D-glucans.
CC {ECO:0000256|RuleBase:RU361166}.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 9 (cellulase E)
CC family. {ECO:0000256|RuleBase:RU361166}.
CC -!- CAUTION: The sequence shown here is derived from an
CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC preliminary data. {ECO:0000313|EMBL:EGC02640.1}.
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DR EMBL; ADKM02000091; EGC02640.1; -; Genomic_DNA.
DR RefSeq; WP_002850623.1; NZ_ADKM02000091.1.
DR ProteinModelPortal; E9SDS5; -.
DR STRING; 246199.CUS_7090; -.
DR EnsemblBacteria; EGC02640; EGC02640; CUS_7090.
DR eggNOG; ENOG4105E08; Bacteria.
DR eggNOG; ENOG410XNTA; LUCA.
DR OrthoDB; POG091H04TS; -.
DR Proteomes; UP000004259; Unassembled WGS sequence.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR CDD; cd02850; E_set_Cellulase_N; 1.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.120.260; -; 1.
DR Gene3D; 2.60.40.10; -; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR004197; Cellulase_Ig-like.
DR InterPro; IPR003305; CenC_carb-bd.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR001701; Glyco_hydro_9.
DR InterPro; IPR033126; Glyco_hydro_9_Asp/Glu_AS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR Pfam; PF02018; CBM_4_9; 1.
DR Pfam; PF02927; CelD_N; 1.
DR Pfam; PF00759; Glyco_hydro_9; 1.
DR SUPFAM; SSF48208; SSF48208; 1.
DR SUPFAM; SSF49785; SSF49785; 1.
DR SUPFAM; SSF81296; SSF81296; 1.
DR PROSITE; PS00698; GLYCOSYL_HYDROL_F9_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|RuleBase:RU361166};
KW Cellulose degradation {ECO:0000256|RuleBase:RU361166};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Complete proteome {ECO:0000313|Proteomes:UP000004259};
KW Glycosidase {ECO:0000256|RuleBase:RU361166};
KW Hydrolase {ECO:0000256|RuleBase:RU361166};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Polysaccharide degradation {ECO:0000256|RuleBase:RU361166};
KW Reference proteome {ECO:0000313|Proteomes:UP000004259};
KW Signal {ECO:0000256|RuleBase:RU361166};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1 24 {ECO:0000256|RuleBase:RU361166}.
FT CHAIN 25 912 Endoglucanase. {ECO:0000256|RuleBase:
FT RU361166}.
FT /FTId=PRO_5005128628.
FT TRANSMEM 869 890 Helical. {ECO:0000256|SAM:Phobius}.
FT DOMAIN 36 176 CBM-cenC. {ECO:0000259|Pfam:PF02018}.
FT DOMAIN 218 295 CelD_N. {ECO:0000259|Pfam:PF02927}.
FT COILED 621 641 {ECO:0000256|SAM:Coils}.
SQ SEQUENCE 912 AA; 99771 MW; 7BC5DBF704718EA5 CRC64;
MSKGILKRVL SAAAAAVLTM NSTAALGVFA GQQLGQTDFD DGVGLPWHIC ESTTGEMDFD
IADGKYKITI VNPGGASNGG EDRWDCQFRH RGLKIVSGHQ YKVSYEITPS NSGKYYTKIG
NLDGDVEVWH NMSNGYDLDS TWDPIPIGAN ETKKVEVTFT ASQNIDVAEW AFHLGGDGQY
TPGGCFPAGT VITFDNMSLI DLTSDENDYV FPEVWQRADI LTNQVGYFAE REKKATLLCT
DKDEVGFELI DESGDSVYEG KSEYFGYDED SEDTVHILDF SDFDGSGTFH IEADNGAVSR
DFKVFAKDEV SDYSAMLYDS LNYFYQNRSG IEIKEEYISS GDKSSLARAA GHTTDNAEIQ
QTWGYSGTSG TVDVTGGWYD AGDHGKYTVN GGLSLWMLQD LYEFFVYTGN EKIFADGSMI
IPESGNGFPD LLDEARWEME WMLKMQIDGG DYSGMAYHKA HDETWTGLGV APADDDKKRI
IKPQTTAATL NLAACAAQSA RLWEDLDKEF SDKCLDAAEK AYEAAKKHPD MYAPLDESVG
GGAYGDNDVT DEFYWAAMEL YVSTGKDNYL KDAEKSDFYM TVPVTLGGGE SVDTVGTFDW
GNTAALGTFT ALLNFESFDD VKKAEKSLKE AADHYLDTEN AQGFGLPYGQ STLSYNDKDK
GYLWGSNSFV ADNAIVLAFA AVMNEDDSYT DGALQGLDYL LGRNAMDYSY VTGYGTHTTE
NPHHRWWSNQ IDDAFPKAPC GVLSGGPNSG MQDPWVRGMG WKKGEIAPQK CYVDHVEAWC
VNECTINWNA SLAWLTAFSA LNAEIKPGEG GKDIGVENDG GGASSTEKTT YDEEKAEENA
AKSGKSAKSR SSAKDADDEN GEGISSTKLV VIIVAAVAVI ILIIATYVFI FEMTKLNRQS
QNNNNGNNGD DK
//
