ID F0EGI8_ENTCA Unreviewed; 1192 AA.
AC F0EGI8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE RecName: Full=Chromosome partition protein Smc {ECO:0000256|HAMAP-Rule:MF_01894};
GN Name=smc {ECO:0000256|HAMAP-Rule:MF_01894,
GN ECO:0000313|EMBL:EGC70908.1};
GN ORFNames=HMPREF9087_0285 {ECO:0000313|EMBL:EGC70908.1};
OS Enterococcus casseliflavus ATCC 12755.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=888066 {ECO:0000313|EMBL:EGC70908.1, ECO:0000313|Proteomes:UP000004835};
RN [1] {ECO:0000313|EMBL:EGC70908.1, ECO:0000313|Proteomes:UP000004835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12755 {ECO:0000313|EMBL:EGC70908.1,
RC ECO:0000313|Proteomes:UP000004835};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for chromosome condensation and partitioning.
CC {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBUNIT: Homodimer. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- DOMAIN: Contains large globular domains required for ATP hydrolysis at
CC each terminus and a third globular domain forming a flexible hinge near
CC the middle of the molecule. These domains are separated by coiled-coil
CC structures. {ECO:0000256|HAMAP-Rule:MF_01894}.
CC -!- SIMILARITY: Belongs to the SMC family. SMC3 subfamily.
CC {ECO:0000256|ARBA:ARBA00005917}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC70908.1}.
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DR EMBL; AEWT01000002; EGC70908.1; -; Genomic_DNA.
DR RefSeq; WP_005232485.1; NZ_GL872323.1.
DR AlphaFoldDB; F0EGI8; -.
DR HOGENOM; CLU_001042_2_2_9; -.
DR Proteomes; UP000004835; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030261; P:chromosome condensation; IEA:InterPro.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-UniRule.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR CDD; cd03278; ABC_SMC_barmotin; 2.
DR Gene3D; 1.20.1060.20; -; 1.
DR Gene3D; 3.30.70.1620; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR HAMAP; MF_01894; Smc_prok; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR003395; RecF/RecN/SMC_N.
DR InterPro; IPR024704; SMC.
DR InterPro; IPR010935; SMC_hinge.
DR InterPro; IPR036277; SMC_hinge_sf.
DR InterPro; IPR011890; SMC_prok.
DR NCBIfam; TIGR02168; SMC_prok_B; 1.
DR PANTHER; PTHR43977; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR PANTHER; PTHR43977:SF1; STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3; 1.
DR Pfam; PF06470; SMC_hinge; 1.
DR Pfam; PF02463; SMC_N; 2.
DR PIRSF; PIRSF005719; SMC; 1.
DR SMART; SM00968; SMC_hinge; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF75553; Smc hinge domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|HAMAP-Rule:MF_01894};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|HAMAP-
KW Rule:MF_01894};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_01894};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_01894}; Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_01894}.
FT DOMAIN 518..637
FT /note="SMC hinge"
FT /evidence="ECO:0000259|SMART:SM00968"
FT COILED 167..201
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 255..345
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 427..468
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT COILED 672..860
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
FT BINDING 32..39
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01894"
SQ SEQUENCE 1192 AA; 134909 MW; 83EBBB5C39781EE1 CRC64;
MYLKRIEIAG FKSFADRTVI DFEHRVTAVV GPNGSGKSNI TEAIRWVLGE QSAKNLRGGK
MPDVIFAGSD TRRALNIAEV TIVLDNSDHY LPMDYSEISV TRRLRRTGES DFFLNKQACR
LKDIQELFMD SGLGKESFSI ISQGKVEAIF SSKPEDRRGI FEEAAGVLKY KQRKKKAEQK
LFETEDNLSR LQDIIYELED QLVPLAAQSD AANRFLALKE KLTTVDVAYA VLEITKAKEA
WETAKAQLST FNQELAQISE KINQGELSLH SLRQQRTAFD ETLERLNQQL LEVTEGLKQA
EGQKEVLDER SKHTQKSSAE YQETLEEVTE RVTLLNEEKA ELIGLLSQKN RSVQEVEAAM
LACQQEQEKY QRSAKEIIEE LRSQYVEAMQ EQATIGNELK YLERQYQQEA AKNQTALSKQ
TQMNTSLKEK TMEAQIVEEQ LTQAKAILEE QRKQYIHLQE KAQTNKKRFD EEQKKMYQLM
SQVQQVRAKQ RSLQDIQENY SGFYQGVRLI LKNKQQISGI VGAVAELIDV PQDYTVAIET
ALGAAAQHVV VENERDARAA ITYLKENRGG RATFLPLTTI KARHLPDYAR NQAKQVSGFI
GVASELVQSP EHIQTITDNL LGSILIAEDL QSANALARAL NYSYRVVSLE GDVMNAGGSM
TGGATKKNAG SLFSQSNELQ QLTAQAAQLD ERLLKTEKQV QHFEAATKEA QAALEELRTQ
GEQARMTEHE LQSRLKNLEN DLSRLKQEQQ VFDFEHREVQ AFFEEYDEKK TSLEEQQKNI
AAQLAKIDQD IHQMNAEEDL IEEKRQTLAQ ESARLQAAFA VQKEQVAHLQ QKIAATNQAL
EENEARQHSL ERQLAALTSN VSDHEFSEEN ILQRIEAFTK TKQQVTAELT VIREQRQVVQ
QEIGALDEAL SAENLTQKEK LSEKTEVEIE KNRAELVMDN RLLYLQEEYN LTFEKAAQDF
PEIEDAEQAK IDIQELKHAI EQIGPVNLNA IEQYEQVNQR HLFLTSQRDD LLSAKAQLFD
TMSEMDEEVK TRFGEVFDAI RLQFKQVFPN MFGGGHAELV LTDPKDLLNT GIEIEAQPPG
KKLQNLSLLS GGERALTAIA LLFSIIQVRP VPFCVLDEVE AALDEANVSR FGHYLSAFQN
DTQFIVVTHR KGTMEAADVL YGVTMQESGV SKTVSVRLEE VREGGSFAAD QA
//
