ID F0EH08_ENTCA Unreviewed; 1614 AA.
AC F0EH08;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Pilin isopeptide linkage domain protein {ECO:0000313|EMBL:EGC70642.1};
DE Flags: Fragment;
GN ORFNames=HMPREF9087_0700 {ECO:0000313|EMBL:EGC70642.1};
OS Enterococcus casseliflavus ATCC 12755.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae;
OC Enterococcus.
OX NCBI_TaxID=888066 {ECO:0000313|EMBL:EGC70642.1, ECO:0000313|Proteomes:UP000004835};
RN [1] {ECO:0000313|EMBL:EGC70642.1, ECO:0000313|Proteomes:UP000004835}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12755 {ECO:0000313|EMBL:EGC70642.1,
RC ECO:0000313|Proteomes:UP000004835};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall
CC {ECO:0000256|ARBA:ARBA00004168}; Peptidoglycan-anchor
CC {ECO:0000256|ARBA:ARBA00004168}.
CC -!- SIMILARITY: Belongs to the serine-aspartate repeat-containing protein
CC (SDr) family. {ECO:0000256|ARBA:ARBA00007257}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC70642.1}.
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DR EMBL; AEWT01000005; EGC70642.1; -; Genomic_DNA.
DR HOGENOM; CLU_000297_3_1_9; -.
DR Proteomes; UP000004835; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0005518; F:collagen binding; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR Gene3D; 2.60.40.1280; -; 1.
DR Gene3D; 2.60.40.3050; -; 4.
DR Gene3D; 2.60.40.740; -; 4.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR008966; Adhesion_dom_sf.
DR InterPro; IPR008456; Collagen-bd_dom.
DR InterPro; IPR011252; Fibrogen-bd_dom1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR041033; Prealbumin-like.
DR InterPro; IPR041171; SDR_Ig.
DR InterPro; IPR022464; Strep_pil_isopept_link.
DR InterPro; IPR038174; Strep_pil_link_sf.
DR NCBIfam; TIGR03786; strep_pil_rpt; 4.
DR PANTHER; PTHR36108:SF13; COLOSSIN-B; 1.
DR PANTHER; PTHR36108; COLOSSIN-B-RELATED; 1.
DR Pfam; PF17961; Big_8; 1.
DR Pfam; PF05737; Collagen_bind; 1.
DR Pfam; PF12892; FctA; 4.
DR Pfam; PF17802; SpaA; 1.
DR SUPFAM; SSF49401; Bacterial adhesins; 5.
PE 3: Inferred from homology;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 154..245
FT /note="SDR-like Ig"
FT /evidence="ECO:0000259|Pfam:PF17961"
FT DOMAIN 865..999
FT /note="Collagen binding"
FT /evidence="ECO:0000259|Pfam:PF05737"
FT DOMAIN 1043..1114
FT /note="Prealbumin-like fold"
FT /evidence="ECO:0000259|Pfam:PF17802"
FT DOMAIN 1135..1238
FT /note="Streptococcal pilin isopeptide linker"
FT /evidence="ECO:0000259|Pfam:PF12892"
FT DOMAIN 1247..1349
FT /note="Streptococcal pilin isopeptide linker"
FT /evidence="ECO:0000259|Pfam:PF12892"
FT DOMAIN 1357..1460
FT /note="Streptococcal pilin isopeptide linker"
FT /evidence="ECO:0000259|Pfam:PF12892"
FT DOMAIN 1468..1571
FT /note="Streptococcal pilin isopeptide linker"
FT /evidence="ECO:0000259|Pfam:PF12892"
FT REGION 34..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1614
FT /evidence="ECO:0000313|EMBL:EGC70642.1"
SQ SEQUENCE 1614 AA; 178918 MW; E446FD9CB43A726D CRC64;
MKKQFSIYIC LLVLLGSILC EPTIILAEAI NATESTERTT ETLESTEPET GTIDTEKAPT
DSSTAGAVQS ETSQAEEEQA TVPSESQATQ ASSTLNQNSI QPRAPDTEAE TEASTTAENL
SANLNERGVQ LFDNVRITDL NDQPFTAENP PMYNGNIKIH FDWSLADTEE IRAGDYYTYQ
LPEYFAIHNT VSGELTRSGG QSIGTFTLAL DGTLTVTFNE AAQTLSNRSG TIDLITELSV
STVTEEVTIH TGIYDEDGHE IIITLPIYEV DIIKTGNVTS GGSVVWEIIF NQTSRELHDV
VITDKMPQGL SYSTSTGYLY DEDTEEWIRT DGLYTYNSVN NTFTFNQTVN QPVRIVINSA
VTDPTASSFK NTATINGSDF TEKTAEATVT YDEQSEYKRF KGYDQETKRA SWEVSVSLDK
DQAQFFDQTY AGSDPEKALH FFVPESLVIT DKDGNPISSE DWSFDETYER KKEGEIVRFS
ITFAKAGYYK IQYDTQLYES VLADTRIYNY ASVRDNQNSS LTGSGTVTPT KMIGVVKTGG
TKDYETKTVP WKIEANTNQQ KVSDLIIEDR YQLISGANSS ALTLLADTLV VTASGVTEPL
ELNNDYTLEL ITETKTLTDG STKELETGFR IKLQGAYQTT SATITANFKT SFDISQHLAL
GSSSTRFSNA AFVYYTDEAG NEFTEASETN TWLDANWVKN ALKYGLFIGE GEDVAKAITA
VFGRNLGTIF DEQTASSDQV YWMGLFNTYK EKINKDAVIT DQLQEGQTLK DLALYTVTVS
GYTTQVRALK EQLVLNEDYS YTYDPDTKTV TITLLKETSE TLAVFLATEA AEDVFTYKNT
ITLTDNDTTL TADGQADKSA KTDWLMKNGS QNAENNRLID WEVMINADSR KIHNAVVTDT
INYNQHTFLR DANDAVIVDV YEAVLNNGTW EKGEKVTFTN EDNPKITSDV VAGTQSLVIA
FEEMIDKPYF IVYQTQLDPG ILNNERVTNN VNLTGSEIEI HTVTKEITIK STDGSGTSSG
TNGSLTIVKY DADGTKERGI DEEAVFQLSR KNAQNTYEVI LSNLVVKNNQ IMENGNAIDR
IDNLRYGDYM IQEITAPEGY ERDATQYTFT ISDKQVNYVF ELANKREIKE TTHALNVQKL
LDGRELKDGE FTFQLVDETG SVILTQTNDG NGQVAFDAIT YNEPGEYHYT IREKAGDDPT
ITYSDKELKV TVIVTEEDNQ LIAKAVYEGN QVFENDYTPK AGSVVLSAEK VLIGRDLKAE
EFDFELINEA GTVLQTKAND AAGKIYFDAL AYDEAGEYHY TIREKAGTDD TITYDAKELA
VVVTVTDEDG QLTAVAEYEG NQVFENDYTP KAGEVVLNAE KVLTGRTLEA NEFAFELVDE
EGNVLQTKTN DATGQIYFDE LTYDEVGEYR YTIREKADAD STITYDMKEI GVVVKVTDED
GQLVAKATYD GNTIFENDYT PKAGEVVLNA EKVLTGRTLE ANEFAFELVD EEGTVLQTKA
NDATGKIYFD ALPYEEAGEY HYTIREKAGT DGTITYDAKE LAVVVTVTDE DGQLTAVAEY
EGNQVFENDY TPKAGGVVLN AEKVLTGRTL EANEFAFELV DEEGTVLQTK ANDA
//
