ID F0F5E9_9BACT Unreviewed; 693 AA.
AC F0F5E9;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 53.
DE SubName: Full=Peptidase family M3 {ECO:0000313|EMBL:EGC20568.1};
DE EC=3.4.-.- {ECO:0000313|EMBL:EGC20568.1};
GN Name=dcp {ECO:0000313|EMBL:EGC20568.1};
GN ORFNames=HMPREF9141_0815 {ECO:0000313|EMBL:EGC20568.1};
OS Prevotella multiformis DSM 16608.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Prevotella.
OX NCBI_TaxID=888743 {ECO:0000313|EMBL:EGC20568.1, ECO:0000313|Proteomes:UP000005697};
RN [1] {ECO:0000313|EMBL:EGC20568.1, ECO:0000313|Proteomes:UP000005697}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 16608 {ECO:0000313|EMBL:EGC20568.1,
RC ECO:0000313|Proteomes:UP000005697};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|RuleBase:RU003435};
CC Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU003435};
CC -!- SIMILARITY: Belongs to the peptidase M3 family.
CC {ECO:0000256|ARBA:ARBA00006040, ECO:0000256|RuleBase:RU003435}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC20568.1}.
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DR EMBL; AEWX01000013; EGC20568.1; -; Genomic_DNA.
DR RefSeq; WP_007368348.1; NZ_GL872283.1.
DR AlphaFoldDB; F0F5E9; -.
DR STRING; 888743.HMPREF9141_0815; -.
DR eggNOG; COG0339; Bacteria.
DR HOGENOM; CLU_001805_4_0_10; -.
DR OrthoDB; 9773538at2; -.
DR Proteomes; UP000005697; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd06456; M3A_DCP; 1.
DR Gene3D; 1.10.1370.40; -; 1.
DR Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR Gene3D; 1.10.1370.10; Neurolysin, domain 3; 1.
DR InterPro; IPR034005; M3A_DCP.
DR InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR InterPro; IPR024077; Neurolysin/TOP_dom2.
DR InterPro; IPR045090; Pept_M3A_M3B.
DR InterPro; IPR001567; Pept_M3A_M3B_dom.
DR PANTHER; PTHR43660; DIPEPTIDYL CARBOXYPEPTIDASE; 1.
DR PANTHER; PTHR43660:SF1; DIPEPTIDYL CARBOXYPEPTIDASE; 1.
DR Pfam; PF01432; Peptidase_M3; 1.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003435};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|RuleBase:RU003435};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW ECO:0000256|RuleBase:RU003435};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003435};
KW Reference proteome {ECO:0000313|Proteomes:UP000005697};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003435}.
FT DOMAIN 240..687
FT /note="Peptidase M3A/M3B catalytic"
FT /evidence="ECO:0000259|Pfam:PF01432"
SQ SEQUENCE 693 AA; 80598 MW; 800803223F486CB4 CRC64;
MTDNISEKKE RTNPFFLPYN TPHDTVPFDR ITLADYEEAM MEGIRREDEQ IEKIIHNPDE
PTFENTIIPE DEVKGRKHYY DLLNRVESVF FNMLSAETND EMDALAQKMS PILTRHANDV
SLNPKLFERI KYVYEHHREL TPEENRLLEN SYDGFVRSGA LLDEAGKNRL RKLTEEASML
SLQFSQNLLK ENKAYTLHIL DKRQLDGLPD TAREAAHEAA KEHGQEGWIF TLDAPSYGPF
MMYSTQRELR KELYMARNTL CIKDKETNNL EVCRRLVNLR REMAQLLGYD TFADYVMKHR
MATTVENVYK LLDDLITAYK PAAIREREEV KALSRELEGD DFKMEPWDAA YYGQQLKKRK
FDLDPEMLRP YFELGNVIKG VFGLATRLYG ITFKENKDIP VYHPDVKPYE VFDKDGSYLA
VLYVDFHPRK GKRDGAWMTE FQGQWIERDG TNVRPHTSLV MNLSKPTEDK PALLRLGEVE
TFLHEFGHSL HGMFANTRFE SLSGTNVWWD FVELPSQFME NFAVEKDFLR TFAFHYQTGE
AMPDELIDKI VASRTFGAAT ACLRQVSFGL LDMAYYTQKD AFTEDIIPFE KKAWASAIID
EQRMDTCMTV QFSHIMAGGY AAGYYSYKWA EVLDADAFSV FKKEGIFNQA TARRFRDNIL
SRGGTEHPMT LYKRFRGQEP TIDALMKRDG ISR
//
