ID F0FFR9_STRSA Unreviewed; 323 AA.
AC F0FFR9;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Topoisomerase DNA-binding C4 zinc finger domain protein {ECO:0000313|EMBL:EGC22334.1};
GN ORFNames=HMPREF9388_1551 {ECO:0000313|EMBL:EGC22334.1};
OS Streptococcus sanguinis SK353.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=888815 {ECO:0000313|EMBL:EGC22334.1, ECO:0000313|Proteomes:UP000004185};
RN [1] {ECO:0000313|EMBL:EGC22334.1, ECO:0000313|Proteomes:UP000004185}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK353 {ECO:0000313|EMBL:EGC22334.1,
RC ECO:0000313|Proteomes:UP000004185};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC22334.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AEWY01000007; EGC22334.1; -; Genomic_DNA.
DR RefSeq; WP_002898513.1; NZ_GL872307.1.
DR AlphaFoldDB; F0FFR9; -.
DR PATRIC; fig|888815.3.peg.1523; -.
DR HOGENOM; CLU_068011_2_0_9; -.
DR Proteomes; UP000004185; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003916; F:DNA topoisomerase activity; IEA:InterPro.
DR GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR Gene3D; 3.30.65.10; Bacterial Topoisomerase I, domain 1; 1.
DR InterPro; IPR011528; NERD.
DR InterPro; IPR013498; Topo_IA_Znf.
DR Pfam; PF08378; NERD; 1.
DR Pfam; PF01396; zf-C4_Topoisom; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS50965; NERD; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000313|EMBL:EGC22334.1};
KW Isomerase {ECO:0000313|EMBL:EGC22334.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..180
FT /note="NERD"
FT /evidence="ECO:0000259|PROSITE:PS50965"
SQ SEQUENCE 323 AA; 37757 MW; 1C578A87C521CDCC CRC64;
MFGFFFVAFV AVFGIVFFIS YKLLEDREDT DSDWSSSQSP EPDYFQQTQT APWELKYNKG
KQGEYQLGQV LNQLYSYKKI LYNLYIFKED GTTTEIDALL IHPSGIYIFE SKNYKGWIFG
SENQQYWTQV LSGGRGKSYK HSFFNPIIQN KVHLKWLNYY LNQYTPNLYS YIVFGNDCQL
KEIHLNSDRH KVIQTWQVIG TIDRQACQSQ VYLSPDQIDD LYRMLLPLTK RKQVIKERHI
NHIAQNKQRR EAEKICPRCQ HGLVLRTAGK GSKAGQKFWG CSNFPRCRFT QKYQEPVCSP
PAAQIPNFGQ PVVQNLNQTQ SNS
//
