ID F0GDK8_9BURK Unreviewed; 699 AA.
AC F0GDK8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Type IV pilus biogenesis and competence protein PilQ {ECO:0000256|ARBA:ARBA00014124};
DE Flags: Fragment;
GN ORFNames=B1M_31662 {ECO:0000313|EMBL:EGD00419.1};
OS Burkholderia sp. TJI49.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia.
OX NCBI_TaxID=987057 {ECO:0000313|EMBL:EGD00419.1, ECO:0000313|Proteomes:UP000003049};
RN [1] {ECO:0000313|EMBL:EGD00419.1, ECO:0000313|Proteomes:UP000003049}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TJI49 {ECO:0000313|EMBL:EGD00419.1,
RC ECO:0000313|Proteomes:UP000003049};
RX PubMed=23653265; DOI=10.1007/s11274-013-1366-5;
RA Khan A., Asif H., Studholme D.J., Khan I.A., Azim M.K.;
RT "Genome characterization of a novel Burkholderia cepacia complex genomovar
RT isolated from dieback affected mango orchards.";
RL World J. Microbiol. Biotechnol. 29:2033-2044(2013).
CC -!- FUNCTION: Required for type IV pilus biogenesis and competence. Could
CC function as a pore for exit of the pilus but also as a channel for
CC entry of heme and antimicrobial agents and uptake of transforming DNA.
CC {ECO:0000256|ARBA:ARBA00024678}.
CC -!- SUBUNIT: Homododecamer. Tetramer of trimer.
CC {ECO:0000256|ARBA:ARBA00025897}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane
CC {ECO:0000256|RuleBase:RU004004}.
CC -!- SIMILARITY: Belongs to the bacterial secretin family. GSP D subfamily.
CC {ECO:0000256|ARBA:ARBA00006980}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGD00419.1}.
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DR EMBL; AEXE01001933; EGD00419.1; -; Genomic_DNA.
DR AlphaFoldDB; F0GDK8; -.
DR Proteomes; UP000003049; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015627; C:type II protein secretion system complex; IEA:InterPro.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR GO; GO:0015628; P:protein secretion by the type II secretion system; IEA:InterPro.
DR Gene3D; 3.30.1370.120; -; 3.
DR InterPro; IPR049371; GspD-like_N0.
DR InterPro; IPR001775; GspD/PilQ.
DR InterPro; IPR005644; NolW-like.
DR InterPro; IPR038591; NolW-like_sf.
DR InterPro; IPR004846; T2SS/T3SS_dom.
DR InterPro; IPR013356; T2SS_GspD.
DR InterPro; IPR004845; T2SS_GspD_CS.
DR NCBIfam; TIGR02517; type_II_gspD; 1.
DR PANTHER; PTHR30332; PROBABLE GENERAL SECRETION PATHWAY PROTEIN D; 1.
DR PANTHER; PTHR30332:SF24; SECRETIN XPSD; 1.
DR Pfam; PF00263; Secretin; 1.
DR Pfam; PF03958; Secretin_N; 3.
DR Pfam; PF21305; type_II_gspD_N0; 1.
DR PRINTS; PR00811; BCTERIALGSPD.
DR PRINTS; PR01032; PHAGEIV.
DR PROSITE; PS00875; T2SP_D; 1.
PE 3: Inferred from homology;
KW Competence {ECO:0000256|ARBA:ARBA00023287};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|RuleBase:RU004004}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..699
FT /note="Type IV pilus biogenesis and competence protein
FT PilQ"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003248162"
FT DOMAIN 25..94
FT /note="GspD-like N0"
FT /evidence="ECO:0000259|Pfam:PF21305"
FT DOMAIN 122..180
FT /note="NolW-like"
FT /evidence="ECO:0000259|Pfam:PF03958"
FT DOMAIN 185..256
FT /note="NolW-like"
FT /evidence="ECO:0000259|Pfam:PF03958"
FT DOMAIN 262..402
FT /note="NolW-like"
FT /evidence="ECO:0000259|Pfam:PF03958"
FT DOMAIN 505..666
FT /note="Type II/III secretion system secretin-like"
FT /evidence="ECO:0000259|Pfam:PF00263"
FT REGION 283..368
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..347
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 699
FT /evidence="ECO:0000313|EMBL:EGD00419.1"
SQ SEQUENCE 699 AA; 72683 MW; 0EC1A14496E205D0 CRC64;
MRRVATTLIV AGIVVSQAAY AQVTLNFVNA DIDQVAKAIG AATGKTIIVD PRVKGQLNLV
AERAVPEDQA LKTLQSALRM QGFALVQDHG VLKVVPEADA KLQGVPTYVG NAPQARGDQV
ITQVFELHNE SANNLLPVLR PLISPNNTVT AYPANNTIVV TDYADNVRRI AQIIAGVDSA
AGAQVQVVPL RNANAIDLAA QLQKMLDPGA IGNSDATLKV SVTADPRTNS LLLRASNGAR
LAAAKRLVQQ LDAPSAVPGN MHVVPLRNAD AVKLAKTLRG MLGKGGNDSG SSASSNDANS
FNQNGSSSSG NFSTGTAGTP PLPSGGLGGS SSSSSSYGGT SSSGGLGNAG LLGGDKDKND
DNQPGGMIQA DAATNSLIIT ASDPVYRNLR AVIDQLDKRR AQVYIEALIV ELNSTTAGQL
GIQWQVASGA LLAGTNLAAT AGSVAGNSII NLTAGTVNSS TGTLTGVGLP ANLSNLNQGL
NIGWLHNMFG VQGLGALLQY FAGVSDANVL STPNLITLDN EEAKIVVGEN VPIPTGSYSN
LTSGTTSNAF NTYDRRDVGL TLHVKPQITE GGILKLQLYT EDSAVDTATT NAQTGPSFTK
RSIQSTILAD NGEVIVLGGL MQDAYNVSNS KVPLLGDIPW IGQLFRSESK QRKKTNLMVF
LRPVIISDRD TAQAVTANRY DYIQGVTGAY KSDNNVIRD
//
