ID F0H0H7_9FIRM Unreviewed; 334 AA.
AC F0H0H7;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Electron transfer flavoprotein subunit alpha {ECO:0000313|EMBL:EGC84144.1};
GN Name=etfA {ECO:0000313|EMBL:EGC84144.1};
GN ORFNames=HMPREF9246_1193 {ECO:0000313|EMBL:EGC84144.1};
OS Anaerococcus hydrogenalis ACS-025-V-Sch4.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC Anaerococcus.
OX NCBI_TaxID=879306 {ECO:0000313|EMBL:EGC84144.1, ECO:0000313|Proteomes:UP000005277};
RN [1] {ECO:0000313|EMBL:EGC84144.1, ECO:0000313|Proteomes:UP000005277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-025-V-Sch4 {ECO:0000313|EMBL:EGC84144.1,
RC ECO:0000313|Proteomes:UP000005277};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|PIRSR:PIRSR000089-1};
CC Note=Binds 1 FAD per dimer. {ECO:0000256|PIRSR:PIRSR000089-1};
CC -!- SIMILARITY: Belongs to the ETF alpha-subunit/FixB family.
CC {ECO:0000256|ARBA:ARBA00005817}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC84144.1}.
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DR EMBL; AEXN01000015; EGC84144.1; -; Genomic_DNA.
DR RefSeq; WP_004817189.1; NZ_AEXN01000015.1.
DR AlphaFoldDB; F0H0H7; -.
DR OrthoDB; 9770286at2; -.
DR Proteomes; UP000005277; Unassembled WGS sequence.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd01715; ETF_alpha; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR InterPro; IPR014730; ETF_a/b_N.
DR InterPro; IPR001308; ETF_a/FixB.
DR InterPro; IPR033947; ETF_alpha_N.
DR InterPro; IPR014731; ETF_asu_C.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR PANTHER; PTHR43153; ELECTRON TRANSFER FLAVOPROTEIN ALPHA; 1.
DR PANTHER; PTHR43153:SF1; ELECTRON TRANSFER FLAVOPROTEIN SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF01012; ETF; 1.
DR Pfam; PF00766; ETF_alpha; 1.
DR PIRSF; PIRSF000089; Electra_flavoP_a; 1.
DR SMART; SM00893; ETF; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|PIRSR:PIRSR000089-1};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000089-1}.
FT DOMAIN 7..192
FT /note="Electron transfer flavoprotein alpha/beta-subunit N-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00893"
FT BINDING 221
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 246..247
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 260..264
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 277..284
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
FT BINDING 298
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000089-1"
SQ SEQUENCE 334 AA; 36027 MW; F97AD0CDD74C07B4 CRC64;
MSENKNLWVI VETKEDGSAV NVGLELMNPG RRMADAIDEK LYAIIIGSNV DKAKEEVKEY
GVDGIITVDN EVYKDYNTEV YADAIYQLVK KHSPNIILIG ATNQGRDLGP RVSARLHTGL
TADCTELDID AETKEVRWTR PAFGGNLMAM ILCPDHRPQM GTVRPGVFSK EAIGAKDDID
VIDEDIKFEG EARTKILDFI PRDEGDDVDL VGAEFIVSGG RGLGDPKNFS LIKDLADALD
GTVGSSRAAV DAGWISHSHQ VGQSGKTVGP KVYIAIGISG AIQHLAGINA ADKVIAINKD
PDAPIFARAD YGIVGDLFEV VPKLTEAIKN KKAN
//
