ID F0H179_9FIRM Unreviewed; 449 AA.
AC F0H179;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=CBS domain-containing protein {ECO:0000259|PROSITE:PS51371};
GN ORFNames=HMPREF9246_1960 {ECO:0000313|EMBL:EGC83754.1};
OS Anaerococcus hydrogenalis ACS-025-V-Sch4.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Peptoniphilaceae;
OC Anaerococcus.
OX NCBI_TaxID=879306 {ECO:0000313|EMBL:EGC83754.1, ECO:0000313|Proteomes:UP000005277};
RN [1] {ECO:0000313|EMBL:EGC83754.1, ECO:0000313|Proteomes:UP000005277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACS-025-V-Sch4 {ECO:0000313|EMBL:EGC83754.1,
RC ECO:0000313|Proteomes:UP000005277};
RA Durkin A.S., Madupu R., Torralba M., Gillis M., Methe B., Sutton G.,
RA Nelson K.E.;
RL Submitted (JAN-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the UPF0053 family.
CC {ECO:0000256|ARBA:ARBA00006337}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EGC83754.1}.
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DR EMBL; AEXN01000027; EGC83754.1; -; Genomic_DNA.
DR RefSeq; WP_004817504.1; NZ_AEXN01000027.1.
DR AlphaFoldDB; F0H179; -.
DR OrthoDB; 9798188at2; -.
DR Proteomes; UP000005277; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR InterPro; IPR005170; Transptr-assoc_dom.
DR PANTHER; PTHR22777; HEMOLYSIN-RELATED; 1.
DR PANTHER; PTHR22777:SF33; UPF0053 PROTEIN YEGH; 1.
DR Pfam; PF00571; CBS; 1.
DR Pfam; PF01595; CNNM; 1.
DR Pfam; PF03471; CorC_HlyC; 1.
DR SMART; SM01091; CorC_HlyC; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
PE 3: Inferred from homology;
KW CBS domain {ECO:0000256|ARBA:ARBA00023122, ECO:0000256|PROSITE-
KW ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 223..283
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 289..346
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
SQ SEQUENCE 449 AA; 51816 MW; 48B70BE9859953E9 CRC64;
MDTEGPYWKL RIFLIVLALI FLNALINMIF SSLTSINHQK LRDMVENGDE KAKDVLKISQ
DQQRLMQSQN FQDAVLSIIT ITYLLLNIKD SLAIFLNRES DFMQLVIMVF MVVLFVVFKR
IFANMIPQRI GIRNPYTISK KTAGFAKFIL FLTKPFVNII NKVTNLIMNI FGIESKAIEK
EVTAEQIKSI VQVGEDQGVL RPLESKMINS IMEFDDVWAE EIMTARPEVF MIDIKDRDRK
YLDEFIKLKH SRIPVYDEEV DNILGIIYTK DYLLEAIDVG IASVDIRKLI KPAFFVPEKI
ETDKLFSQMQ KDHTHMAILI DEYGGFSGIV TMEDLVEEIV GDMDDTFDKD LPDIRTSTKG
SYIVKGSTSI KDLNDILGLD IDEENDQYDT VGGFIIDKLG FIPDDDCDQA VIYKNYEFKI
LYIEETRIKI VRIKKINKSD QNLDENIKK
//
