ID   F0IQT6_STRSA            Unreviewed;       325 AA.
AC   F0IQT6;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Competence protein CglB {ECO:0000313|EMBL:EGD39633.1};
GN   Name=cglB {ECO:0000313|EMBL:EGD39633.1};
GN   ORFNames=HMPREF9384_0198 {ECO:0000313|EMBL:EGD39633.1};
OS   Streptococcus sanguinis SK160.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=888812 {ECO:0000313|EMBL:EGD39633.1, ECO:0000313|Proteomes:UP000004562};
RN   [1] {ECO:0000313|EMBL:EGD39633.1, ECO:0000313|Proteomes:UP000004562}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK160 {ECO:0000313|EMBL:EGD39633.1,
RC   ECO:0000313|Proteomes:UP000004562};
RA   Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA   Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA   Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA   Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA   Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA   Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA   Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA   Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA   Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA   Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA   Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the GSP F family.
CC       {ECO:0000256|ARBA:ARBA00005745}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGD39633.1}.
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DR   EMBL; AEXZ01000004; EGD39633.1; -; Genomic_DNA.
DR   AlphaFoldDB; F0IQT6; -.
DR   PATRIC; fig|888812.3.peg.191; -.
DR   HOGENOM; CLU_035032_1_0_9; -.
DR   Proteomes; UP000004562; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.81.30; Type II secretion system (T2SS), domain F; 2.
DR   InterPro; IPR003004; GspF/PilC.
DR   InterPro; IPR018076; T2SS_GspF_dom.
DR   InterPro; IPR042094; T2SS_GspF_sf.
DR   InterPro; IPR047692; T4P_ComGB.
DR   NCBIfam; NF041012; T4P_ComGB; 1.
DR   PANTHER; PTHR30012; GENERAL SECRETION PATHWAY PROTEIN; 1.
DR   PANTHER; PTHR30012:SF0; TYPE II SECRETION SYSTEM PROTEIN F-RELATED; 1.
DR   Pfam; PF00482; T2SSF; 2.
DR   PRINTS; PR00812; BCTERIALGSPF.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        104..126
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        146..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        293..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          11..128
FT                   /note="Type II secretion system protein GspF"
FT                   /evidence="ECO:0000259|Pfam:PF00482"
FT   DOMAIN          196..316
FT                   /note="Type II secretion system protein GspF"
FT                   /evidence="ECO:0000259|Pfam:PF00482"
SQ   SEQUENCE   325 AA;  36873 MW;  FFFC718C7ED24E14 CRC64;
     MSTPKQKKII ELFHNLFSSG FHLAEIVDFL RRSALLEEVY VAEMQAGLSA GQSFSEIVSR
     LGFSDSVVTQ LSLSELHGNL TLSLGKIETY LENLSKVKKK LIEVGTYPLM LLGFLVLIML
     GLRNYLLPQL DSQNLATRLI NHLPQIFLWS SFALAVLVSV ALFYYRKSSK IRFFSKLAAL
     PFIGRLVQAY LTAYYAREWG NMIGQGLELS QIFAIMQEQP SQLFQEIGED MAAALQGGQG
     YADKVASYPF FKKELSLMIE YGEVKSKLGS ELEVYAEKTW EEFFLRINRA MNFIQPLVFI
     FVALVIVLLY AAMLLPIYQN MEVHL
//