ID   F0IVS7_STRSA            Unreviewed;       316 AA.
AC   F0IVS7;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Diacylglycerol kinase catalytic domain protein {ECO:0000313|EMBL:EGD37942.1};
DE            EC=2.7.1.107 {ECO:0000313|EMBL:EGD37942.1};
GN   ORFNames=HMPREF9384_1939 {ECO:0000313|EMBL:EGD37942.1};
OS   Streptococcus sanguinis SK160.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=888812 {ECO:0000313|EMBL:EGD37942.1, ECO:0000313|Proteomes:UP000004562};
RN   [1] {ECO:0000313|EMBL:EGD37942.1, ECO:0000313|Proteomes:UP000004562}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK160 {ECO:0000313|EMBL:EGD37942.1,
RC   ECO:0000313|Proteomes:UP000004562};
RA   Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA   Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA   Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA   Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA   Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA   Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA   Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA   Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA   Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA   Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA   Petrosino J., Highlander S., Gibbs R.;
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- SIMILARITY: Belongs to the diacylglycerol/lipid kinase family.
CC       {ECO:0000256|ARBA:ARBA00005983}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EGD37942.1}.
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DR   EMBL; AEXZ01000011; EGD37942.1; -; Genomic_DNA.
DR   RefSeq; WP_002912818.1; NZ_GL872447.1.
DR   AlphaFoldDB; F0IVS7; -.
DR   PATRIC; fig|888812.3.peg.1912; -.
DR   HOGENOM; CLU_045532_1_0_9; -.
DR   Proteomes; UP000004562; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004143; F:ATP-dependent diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008654; P:phospholipid biosynthetic process; IEA:InterPro.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.200.40; -; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR005218; Diacylglycerol/lipid_kinase.
DR   InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   InterPro; IPR045540; YegS/DAGK_C.
DR   NCBIfam; TIGR00147; YegS/Rv2252/BmrU family lipid kinase; 1.
DR   PANTHER; PTHR12358:SF115; DIACYLGLYCEROL KINASE; 1.
DR   PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR   Pfam; PF00781; DAGK_cat; 1.
DR   Pfam; PF19279; YegS_C; 1.
DR   SMART; SM00046; DAGKc; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR   PROSITE; PS50146; DAGK; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EGD37942.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EGD37942.1}.
FT   DOMAIN          3..138
FT                   /note="DAGKc"
FT                   /evidence="ECO:0000259|PROSITE:PS50146"
SQ   SEQUENCE   316 AA;  34504 MW;  D899CFFB81777596 CRC64;
     MKDKIKRARL IYNPTSGQEI IKKNIAEVLD VLEDVGYETS AYQTTPAPLS AQKEAERAAK
     AGFDLIIAAG GDGTINEVVN GVANLDERPN LAFIPTGTTN DYARALKIPM GDPVAAARII
     EKNQTIKMDI GRAYGSKYFI NIAAAGTLTE LTYSVPSEVK SRLGYFAYVA EGAKKLPRSK
     FRKVRIKHDH GVFEGKISLM FAALTNSIGG FEKLAPDTKL DDGNFTLILV KTANLFDMLS
     LMMQAINGGQ HVGDINVEYL KTSKLQLEVL DKKGPFMLNL DGEYGGDTPV ELEVLHGHLE
     FFANIDEISQ TALSIE
//