ID F0J9T0_AMBVA Unreviewed; 98 AA.
AC F0J9T0;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Kunitz-like protease inhibitor {ECO:0000313|EMBL:DAA34606.1};
OS Amblyomma variegatum (Tropical bont tick).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; Acari;
OC Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Amblyomminae; Amblyomma.
OX NCBI_TaxID=34610 {ECO:0000313|EMBL:DAA34606.1};
RN [1] {ECO:0000313|EMBL:DAA34606.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Amb_var-114 {ECO:0000313|EMBL:DAA34606.1};
RC TISSUE=Salivary gland {ECO:0000313|EMBL:DAA34606.1};
RX PubMed=21362191; DOI=10.1186/1471-2164-12-136;
RA Ribeiro J.M., Anderson J.M., Manoukis N.C., Meng Z., Francishetti I.M.;
RT "A further insight into the sialome of the tropical bont tick, Amblyomma
RT variegatum.";
RL BMC Genomics 12:136-136(2011).
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DR EMBL; BK007631; DAA34606.1; -; mRNA.
DR AlphaFoldDB; F0J9T0; -.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR GO; GO:0044562; P:envenomation resulting in negative regulation of voltage-gated potassium channel activity in another organism; IEA:UniProt.
DR CDD; cd00109; Kunitz-type; 1.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR PANTHER; PTHR10083; KUNITZ-TYPE PROTEASE INHIBITOR-RELATED; 1.
DR Pfam; PF00014; Kunitz_BPTI; 1.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 1.
DR SUPFAM; SSF57362; BPTI-like; 1.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 1.
PE 2: Evidence at transcript level;
KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..98
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003255239"
FT DOMAIN 28..81
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
SQ SEQUENCE 98 AA; 11159 MW; 42622542679A7F79 CRC64;
MHIHLFVLLT ACGLTFTYDA GEERPMVCYL QPEEGRCNNQ PPNVPRWYFD PRYGYCGPFE
WGGCAGNANN FPNCTQCMSV CTDHPQPRQI CRDALHAD
//
