ID F0KK80_ACICP Unreviewed; 299 AA.
AC F0KK80;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Dihydrodipicolinate synthetase {ECO:0000313|EMBL:ADY81255.1};
GN Name=dapA {ECO:0000313|EMBL:ADY81255.1};
GN OrderedLocusNames=BDGL_000669 {ECO:0000313|EMBL:ADY81255.1};
OS Acinetobacter calcoaceticus (strain PHEA-2).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter; Acinetobacter calcoaceticus/baumannii complex.
OX NCBI_TaxID=871585 {ECO:0000313|EMBL:ADY81255.1, ECO:0000313|Proteomes:UP000007477};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=PHEA-2;
RA Zhan Y., Yan Y., Zhang W., Chen M., Ping S., Lu W., Lin M.;
RT "The genome sequence of a nonpathogenic wastewater-adapted bacterium
RT Acinetobacter calcoaceticus PHEA-2 and comparative genomics insights into
RT environmental adaptation.";
RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADY81255.1, ECO:0000313|Proteomes:UP000007477}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PHEA-2 {ECO:0000313|EMBL:ADY81255.1,
RC ECO:0000313|Proteomes:UP000007477};
RX PubMed=21441526; DOI=10.1128/JB.00261-11;
RA Zhan Y., Yan Y., Zhang W., Yu H., Chen M., Lu W., Ping S., Peng Z.,
RA Yuan M., Zhou Z., Elmerich C., Lin M.;
RT "Genome sequence of Acinetobacter calcoaceticus PHEA-2, isolated from
RT industry wastewater.";
RL J. Bacteriol. 193:2672-2673(2011).
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
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DR EMBL; CP002177; ADY81255.1; -; Genomic_DNA.
DR RefSeq; WP_014206383.1; NC_016603.1.
DR RefSeq; YP_004994937.1; NC_016603.1.
DR AlphaFoldDB; F0KK80; -.
DR STRING; 871585.BDGL_000669; -.
DR GeneID; 11638849; -.
DR KEGG; acc:BDGL_000669; -.
DR PATRIC; fig|871585.3.peg.668; -.
DR eggNOG; COG0329; Bacteria.
DR HOGENOM; CLU_075248_0_0_6; -.
DR OrthoDB; 6142028at2; -.
DR Proteomes; UP000007477; Chromosome.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF74; BLL4423 PROTEIN; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000007477}.
FT ACT_SITE 123
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 151
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 196
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 299 AA; 32589 MW; D94274B4E690667D CRC64;
MTPCTPNREP DFDALVKKGH ELIEAGMSAV VYCGSMGDWP LLTEAQRQEG VARLVAAGIP
TIVGTGAVNS KEAVSHAAHA EKVGAQGLMV IPRVLSRGAS PTAQKAHFSA ILKAAPSLPA
VIYNSPYYGF ATRADLFFEL RREFPNLIGF KEFGGAADMR YAAEFITSQD DSVTLMAGVD
TQVFHGFVNC NATGAITGIG NALPKEVLQL VDLSKKAAAG DAQARRLAQE LSSALEVLSS
FDEGTDLVLY YKYLMVLNGD KEYTLHFNET DALSESQRKY VETQYELFRT WYRNWSAEI
//
