ID F0NJ49_SULIH Unreviewed; 444 AA.
AC F0NJ49;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Phosphomethylpyrimidine kinase {ECO:0000313|EMBL:ADX81563.1};
GN OrderedLocusNames=SiH_0191 {ECO:0000313|EMBL:ADX81563.1};
OS Sulfolobus islandicus (strain HVE10/4).
OC Archaea; Thermoproteota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC Sulfolobus.
OX NCBI_TaxID=930943 {ECO:0000313|EMBL:ADX81563.1, ECO:0000313|Proteomes:UP000006395};
RN [1] {ECO:0000313|EMBL:ADX81563.1, ECO:0000313|Proteomes:UP000006395}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HVE10/4 {ECO:0000313|EMBL:ADX81563.1,
RC ECO:0000313|Proteomes:UP000006395};
RX PubMed=21278296; DOI=10.1128/JB.01487-10;
RA Guo L., Brugger K., Liu C., Shah S.A., Zheng H., Zhu Y., Wang S.,
RA Lillestol R.K., Chen L., Frank J., Prangishvili D., Paulin L., She Q.,
RA Huang L., Garrett R.A.;
RT "Genome analyses of icelandic strains of Sulfolobus islandicus, model
RT organisms for genetic and virus-host interaction studies.";
RL J. Bacteriol. 193:1672-1680(2011).
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DR EMBL; CP002426; ADX81563.1; -; Genomic_DNA.
DR RefSeq; WP_014511846.1; NC_017275.1.
DR AlphaFoldDB; F0NJ49; -.
DR GeneID; 78427362; -.
DR KEGG; sih:SiH_0191; -.
DR HOGENOM; CLU_035788_0_0_2; -.
DR Proteomes; UP000006395; Chromosome.
DR GO; GO:0008972; F:phosphomethylpyrimidine kinase activity; IEA:InterPro.
DR GO; GO:0004789; F:thiamine-phosphate diphosphorylase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009228; P:thiamine biosynthetic process; IEA:InterPro.
DR CDD; cd01169; HMPP_kinase; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR Gene3D; 3.40.225.10; Class II aldolase/adducin N-terminal domain; 1.
DR InterPro; IPR036409; Aldolase_II/adducin_N_sf.
DR InterPro; IPR004399; HMP/HMP-P_kinase_dom.
DR InterPro; IPR013749; PM/HMP-P_kinase-1.
DR InterPro; IPR029056; Ribokinase-like.
DR InterPro; IPR019293; ThiN.
DR NCBIfam; TIGR00097; HMP-P_kinase; 1.
DR PANTHER; PTHR20858:SF17; HYDROXYMETHYLPYRIMIDINE_PHOSPHOMETHYLPYRIMIDINE KINASE THI20-RELATED; 1.
DR PANTHER; PTHR20858; PHOSPHOMETHYLPYRIMIDINE KINASE; 1.
DR Pfam; PF08543; Phos_pyr_kin; 1.
DR Pfam; PF10120; ThiP_synth; 1.
DR SUPFAM; SSF53639; AraD/HMP-PK domain-like; 1.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ADX81563.1};
KW Transferase {ECO:0000313|EMBL:ADX81563.1}.
FT DOMAIN 13..253
FT /note="Pyridoxamine kinase/Phosphomethylpyrimidine kinase"
FT /evidence="ECO:0000259|Pfam:PF08543"
SQ SEQUENCE 444 AA; 50178 MW; 93ED10AB10E75461 CRC64;
MIKPVGMTVA GLDTGNGAGG ETDLRVFEVL GIHGVFAITA ITAQSTKGIK DINVVSSEFL
KKQIETLLDD FNVEAVKMGM IYTKEQFQVV NELLHDSFLV VDPVLYAKDG TPLIKDVEDY
KKIILPIAKV ITPNIIEASA ISGIKVEKES DVVIACKKIR ETYNIAHVII KGGHSKGDFS
FDYMCNEEGV YKIGYHRIQA KDTHGTGSVF ATAFTAEYIK TKDVKLAFRK ARDFVQSPIE
YGLNIGKGVG PVNVSIEIMK KSMKYEVVEE MRRFAEFAEN NEKFWILIPE VQSNLAHSIK
PEYVRDLNDI ATFRGRIIRR WDKKVIVGHP VVFGNPTHTA RMLLSIILKG MNSTCLMNIR
YDDKIVESFK EIGYETVEIN RELEPSHGEG KTMQWIIEYI SGEYVRIPNV IYDKGTKGKE
AMIRFWTKNM EEMIEALDKL LKML
//
