ID F0NS81_LACHH Unreviewed; 215 AA.
AC F0NS81;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Deoxyadenosine kinase {ECO:0000313|EMBL:ADX71175.1};
GN OrderedLocusNames=LBHH_2010 {ECO:0000313|EMBL:ADX71175.1};
OS Lactobacillus helveticus (strain H10).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=767462 {ECO:0000313|EMBL:ADX71175.1, ECO:0000313|Proteomes:UP000008640};
RN [1]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=H10;
RA Zhang H., Zhao W., Chen Y., Sun Z., Sun T., Meng H.;
RT "Complete genome sequence of Lactobacillus helveticus strain H10.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADX71175.1, ECO:0000313|Proteomes:UP000008640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H10 {ECO:0000313|EMBL:ADX71175.1,
RC ECO:0000313|Proteomes:UP000008640};
RX PubMed=21398542; DOI=10.1128/JB.00166-11;
RA Zhao W., Chen Y., Sun Z., Wang J., Zhou Z., Sun T., Wang L., Chen W.,
RA Zhang H.;
RT "Complete genome sequence of Lactobacillus helveticus H10.";
RL J. Bacteriol. 193:2666-2667(2011).
CC -!- SIMILARITY: Belongs to the DCK/DGK family.
CC {ECO:0000256|ARBA:ARBA00007420}.
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DR EMBL; CP002429; ADX71175.1; -; Genomic_DNA.
DR RefSeq; WP_014564390.1; NC_017467.1.
DR AlphaFoldDB; F0NS81; -.
DR KEGG; lhl:LBHH_2010; -.
DR PATRIC; fig|767462.3.peg.2270; -.
DR HOGENOM; CLU_030466_2_1_9; -.
DR Proteomes; UP000008640; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019136; F:deoxynucleoside kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd01673; dNK; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002624; DCK/DGK.
DR InterPro; IPR031314; DNK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10513; DEOXYNUCLEOSIDE KINASE; 1.
DR PANTHER; PTHR10513:SF15; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX SUBUNIT 10, MITOCHONDRIAL; 1.
DR Pfam; PF01712; dNK; 1.
DR PIRSF; PIRSF000705; DNK; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Kinase {ECO:0000313|EMBL:ADX71175.1};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR000705-3};
KW Transferase {ECO:0000313|EMBL:ADX71175.1}.
FT DOMAIN 5..209
FT /note="Deoxynucleoside kinase"
FT /evidence="ECO:0000259|Pfam:PF01712"
FT ACT_SITE 79
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-1"
FT BINDING 9..17
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 141..145
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
FT BINDING 189..191
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR000705-3"
SQ SEQUENCE 215 AA; 24717 MW; 8DCA50B20C051FF3 CRC64;
MIQVIVLSGP IGAGKSSLTS ILAEHLGTQA FYEGVDSNPV LPLYYKDMKR YTFLLNTYLL
NHRLAQINQA IQDKNSVSDR SIYEDALFFK MNADSKVADP TEFKIYDDLL ENMIEDTPGN
PSKKPDLLIY IHVSLDTMLD RIKKRGRSFE QISTDPGLKD YYARLLRYYE PWYEQYDASP
KMAINGDKLD FVSSMDAQRE VLKEIDEKLH EIGNL
//
