ID   F0RWX0_SPHGB            Unreviewed;       920 AA.
AC   F0RWX0;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=5'-nucleotidase {ECO:0000313|EMBL:ADY13751.1};
DE            EC=3.1.3.5 {ECO:0000313|EMBL:ADY13751.1};
GN   OrderedLocusNames=SpiBuddy_1928 {ECO:0000313|EMBL:ADY13751.1};
OS   Sphaerochaeta globosa (strain ATCC BAA-1886 / DSM 22777 / Buddy)
OS   (Spirochaeta sp. (strain Buddy)).
OC   Bacteria; Spirochaetota; Spirochaetia; Spirochaetales; Sphaerochaetaceae;
OC   Sphaerochaeta.
OX   NCBI_TaxID=158189 {ECO:0000313|EMBL:ADY13751.1, ECO:0000313|Proteomes:UP000008466};
RN   [1] {ECO:0000313|Proteomes:UP000008466}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-1886 / DSM 22777 / Buddy
RC   {ECO:0000313|Proteomes:UP000008466};
RA   Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA   Zeytun A., Detter J.C., Han C., Tapia R., Land M., Hauser L., Kyrpides N.,
RA   Ivanova N., Mikhailova N., Pagani I., Ritalahti K.M., Loeffler F.E.,
RA   Woyke T.;
RT   "Complete sequence of Spirochaeta sp. Buddy.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP002541; ADY13751.1; -; Genomic_DNA.
DR   RefSeq; WP_013607600.1; NC_015152.1.
DR   AlphaFoldDB; F0RWX0; -.
DR   STRING; 158189.SpiBuddy_1928; -.
DR   KEGG; sbu:SpiBuddy_1928; -.
DR   eggNOG; COG0737; Bacteria.
DR   HOGENOM; CLU_312128_0_0_12; -.
DR   OrthoDB; 9800780at2; -.
DR   Proteomes; UP000008466; Chromosome.
DR   GO; GO:0106411; F:XMP 5'-nucleosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009166; P:nucleotide catabolic process; IEA:InterPro.
DR   Gene3D; 3.60.21.10; -; 2.
DR   Gene3D; 3.90.780.10; 5'-Nucleotidase, C-terminal domain; 1.
DR   InterPro; IPR008334; 5'-Nucleotdase_C.
DR   InterPro; IPR036907; 5'-Nucleotdase_C_sf.
DR   InterPro; IPR006179; 5_nucleotidase/apyrase.
DR   InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR   InterPro; IPR029052; Metallo-depent_PP-like.
DR   PANTHER; PTHR11575:SF48; 5' NUCLEOTIDASE, ECTO-LIKE; 1.
DR   PANTHER; PTHR11575; 5'-NUCLEOTIDASE-RELATED; 1.
DR   Pfam; PF02872; 5_nucleotid_C; 1.
DR   Pfam; PF00149; Metallophos; 1.
DR   PRINTS; PR01607; APYRASEFAMLY.
DR   SUPFAM; SSF55816; 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain; 1.
DR   SUPFAM; SSF56300; Metallo-dependent phosphatases; 2.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:ADY13751.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008466};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           29..920
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5003255665"
FT   DOMAIN          443..655
FT                   /note="Calcineurin-like phosphoesterase"
FT                   /evidence="ECO:0000259|Pfam:PF00149"
FT   DOMAIN          745..896
FT                   /note="5'-Nucleotidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02872"
SQ   SEQUENCE   920 AA;  96723 MW;  298E63F3CCD352F0 CRC64;
     MKRLSRTIMT AMLVALLAFS LVGCKSTAKV EPIPPAPVVE TAPEPVAPVA PVPEPAPAPV
     APAPAPVAPA PAPAPAPAPV VAEPVEIELP YGVKEIVKND DGAKAFDLFI VHTNDLNGNI
     YAENGGLGLA KFSTALKAGR AISDNWLLLN SGNVGEVPAQ AAMLAAEVVD ELGYDAYTPQ
     AIQLATGIAG TKKAIPLSAN ALDANGYLVA QPYQIYDFNG FKVGVAGLVA PKPIQGVSFT
     SDIILDSAQY AVDLAKGYVD YLVILSDLGD EGLITSEMVA QNIDGIDLIV DGNGSAKAKT
     VNGTLIVRAD EQLKSVGAVQ LSVVNGEVKA VYPMLLPVAD VLEPAKSAIA KTYEPFARAM
     GYTLMVTVPE DPAIVAKIGA TPVKKAAVPA PAPAPAPAPA PAPVAPAPAP APVVAAPKAV
     EYPLGVTEIV KNDAGTAEFD LFIVHSNDVH ARIVPADGGM GYSKLSTMLK MGRALTDNIL
     VLDAGDVTHG TNLANMFEGE TVGVLLDTLG YDAVAPGNHD FNYGADRLIE AAKFAEEYTD
     LKVLSANVLD ENGYLLFQPY QVYNFNGFKI AVVGLTTPDT ATKTHPKNVE GITFANEEIF
     EIGQMAIDMA KQYVDYIIVL GHIGMDPDGA SGLTTDKIVS KIKGIDLFVD GHSHTLLKEG
     MKIGDTLVVQ TGDYLKNLGL VQLHVKNGKV TATYPMLIPA ADVLNAKDSA LAKQYGISDI
     PNDPQVDEYV GYMSAQLSEK LNTLVATLPE NLDGERANVR TKATNLSKLI TMAMTAESGA
     DFTITNGGGI RASLKAGNVT MGDVINVLPF TNIITVVEVK GSDVYAALEH GYSKLPEQNG
     AFSQTDLQVV YNRFAAPGKR ILRVLLNGKA IDRNATYKVA TNDFMAAGGD GYTMFGKVLT
     EGSLLSDVFI EFLKKSYPVK
//