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Database: UniProt
Entry: F0SKZ2_RUBBR
LinkDB: F0SKZ2_RUBBR
Original site: F0SKZ2_RUBBR 
ID   F0SKZ2_RUBBR            Unreviewed;       341 AA.
AC   F0SKZ2;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   07-JUN-2017, entry version 42.
DE   SubName: Full=Chromosomal replication initiator DnaA domain protein {ECO:0000313|EMBL:ADY59845.1};
GN   OrderedLocusNames=Plabr_2243 {ECO:0000313|EMBL:ADY59845.1};
OS   Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 /
OS   NBRC 103401 / IFAM 1448) (Planctomyces brasiliensis).
OC   Bacteria; Planctomycetes; Planctomycetia; Planctomycetales;
OC   Planctomycetaceae; Rubinisphaera.
OX   NCBI_TaxID=756272 {ECO:0000313|EMBL:ADY59845.1, ECO:0000313|Proteomes:UP000006860};
RN   [1] {ECO:0000313|Proteomes:UP000006860}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49424 / DSM 5305 / JCM 21570 / NBRC 103401 / IFAM 1448
RC   {ECO:0000313|Proteomes:UP000006860};
RA   Lucas S., Copeland A., Lapidus A., Bruce D., Goodwin L., Pitluck S.,
RA   Kyrpides N., Mavromatis K., Pagani I., Ivanova N., Ovchinnikova G.,
RA   Lu M., Detter J.C., Han C., Land M., Hauser L., Markowitz V.,
RA   Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Tindall B.,
RA   Pomrenke H.G., Brambilla E., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Planctomyces brasiliensis DSM 5305.";
RL   Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|SAAS:SAAS00731907}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family.
CC       {ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP002546; ADY59845.1; -; Genomic_DNA.
DR   RefSeq; WP_013628569.1; NC_015174.1.
DR   STRING; 756272.Plabr_2243; -.
DR   EnsemblBacteria; ADY59845; ADY59845; Plabr_2243.
DR   KEGG; pbs:Plabr_2243; -.
DR   eggNOG; ENOG410851T; Bacteria.
DR   eggNOG; COG0593; LUCA.
DR   KO; K02313; -.
DR   OrthoDB; POG091H02FF; -.
DR   Proteomes; UP000006860; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:InterPro.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000006860};
KW   Cytoplasm {ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|RuleBase:RU004227,
KW   ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006860}.
FT   DOMAIN      243    312       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
SQ   SEQUENCE   341 AA;  38121 MW;  1BFDDE775A0B0A68 CRC64;
     MGTQFEHDFI PLPENEFAVA AVERLFAETP AIDPPLLFLF GPSGAGKSHL VMQALEAFHH
     RYEGVRQRTL SAYEFATLNM ESAAGEEETA AQLEELADLD VFVCEGVQHF DRQTWLQKKL
     ILLIDDILRS GGRVILTSQL PVGAYEQTHP KLVSRFHSGV TASMAMPGVE SRKRLIQYFA
     AIHDLEIHPT AVEQLARKMP VSPREMHGAI VQLEAVQRLE EREIDNGTVE ELLAFQQPRN
     VPSMTDVARS VAKEFGVTVR SIRSPARAQT LLIPRQVAML LSRELIQANY SDIGAYYGGR
     SHSTVMHACQ ALTRKSSGSP ELDYRVCQLR RVLQGQPIKP R
//
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