ID F0T6A8_METLA Unreviewed; 328 AA.
AC F0T6A8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Cysteine synthase A {ECO:0000313|EMBL:ADZ09423.1};
DE EC=2.5.1.47 {ECO:0000313|EMBL:ADZ09423.1};
GN OrderedLocusNames=Metbo_1179 {ECO:0000313|EMBL:ADZ09423.1};
OS Methanobacterium lacus (strain AL-21).
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobacterium.
OX NCBI_TaxID=877455 {ECO:0000313|EMBL:ADZ09423.1, ECO:0000313|Proteomes:UP000007490};
RN [1] {ECO:0000313|Proteomes:UP000007490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AL-21 {ECO:0000313|Proteomes:UP000007490};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S.,
RA Chertkov O., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Ivanova N., Mikhailova N., Pagani I., Cadillo-Quiroz H.,
RA Imachi H., Zinder S., Liu W., Woyke T.;
RT "Complete sequence of Methanobacterium sp. AL-21.";
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADZ09423.1, ECO:0000313|Proteomes:UP000007490}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AL-21 {ECO:0000313|EMBL:ADZ09423.1,
RC ECO:0000313|Proteomes:UP000007490};
RX PubMed=24449792; DOI=10.1099/ijs.0.059964-0;
RA Cadillo-Quiroz H., Brauer S.L., Goodson N., Yavitt J.B., Zinder S.H.;
RT "Methanobacterium paludis sp. nov. and a novel strain of Methanobacterium
RT lacus isolated from northern peatlands.";
RL Int. J. Syst. Evol. Microbiol. 64:1473-1480(2014).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
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DR EMBL; CP002551; ADZ09423.1; -; Genomic_DNA.
DR RefSeq; WP_013644774.1; NC_015216.1.
DR AlphaFoldDB; F0T6A8; -.
DR SMR; F0T6A8; -.
DR STRING; 877455.Metbo_1179; -.
DR GeneID; 10277629; -.
DR KEGG; mel:Metbo_1179; -.
DR eggNOG; arCOG01430; Archaea.
DR HOGENOM; CLU_021018_1_0_2; -.
DR OrthoDB; 10138at2157; -.
DR Proteomes; UP000007490; Chromosome.
DR GO; GO:0004124; F:cysteine synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR CDD; cd01561; CBS_like; 1.
DR Gene3D; 3.40.50.1100; -; 2.
DR InterPro; IPR005856; Cys_synth.
DR InterPro; IPR005859; CysK.
DR InterPro; IPR001926; TrpB-like_PALP.
DR InterPro; IPR036052; TrpB-like_PALP_sf.
DR NCBIfam; TIGR01139; cysK; 1.
DR NCBIfam; TIGR01136; cysKM; 1.
DR PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR PANTHER; PTHR10314:SF194; CYSTATHIONINE BETA-SYNTHASE; 1.
DR Pfam; PF00291; PALP; 1.
DR SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007490};
KW Transferase {ECO:0000313|EMBL:ADZ09423.1}.
FT DOMAIN 15..302
FT /note="Tryptophan synthase beta chain-like PALP"
FT /evidence="ECO:0000259|Pfam:PF00291"
SQ SEQUENCE 328 AA; 34597 MW; 638A2B8876C1320D CRC64;
MVNIPKLTRG IANDITETIG NTPLVRLNKL TEGSKAEVLV KVESFNPLSS VKDRIGVAMI
EAGEEAGVIK ENTILIEPTS GNTGIALAFV AAAKGYKLIL TMPDTMSIER RKLLALLGAE
IVLTPGANGM PGAVAKAEEL AAEIPGAVMP QQFKNIANPK IHRETTAQEI WRDTDGKVDV
LVSGTGTGGT ITGVATALKE LKPEFKAVAV EPVTSPVLSG GSPGPHKIQG IGPGFIPDVL
QTEIIDEIVQ VSDDDAAQTL LKLAREEGIL AGISSGAAVF AALQLAKKDE YAGKQIVVIL
PDTGERYLSM DWVFEDIFKS SESSDFTN
//
