ID F0U5U9_AJEC8 Unreviewed; 366 AA.
AC F0U5U9;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Mitochondrial export translocase Oxa2 {ECO:0000313|EMBL:EGC42184.1};
GN Name=OXA2 {ECO:0000313|EMBL:QSS51398.1};
GN ORFNames=HCEG_01546 {ECO:0000313|EMBL:EGC42184.1}, I7I53_06710
GN {ECO:0000313|EMBL:QSS51398.1};
OS Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS capsulatum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN [1] {ECO:0000313|Proteomes:UP000008142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:EGC42184.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=H88 {ECO:0000313|EMBL:EGC42184.1};
RG The Broad Institute Genome Sequencing Platform;
RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT "Annotation of Ajellomyces capsulatus strain H88.";
RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QSS51398.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=H88 {ECO:0000313|EMBL:QSS51398.1};
RA Voorhies M., Cohen S., Shea T.P., Petrus S., Munoz J.F., Poplawski S.,
RA Goldman W.E., Michael T., Cuomo C.A., Sil A., Beyhan S.;
RT "Chromosome-level genome assembly of a human fungal pathogen reveals
RT clustering of transcriptionally co-regulated genes.";
RL Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family.
CC {ECO:0000256|ARBA:ARBA00009877}.
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DR EMBL; DS990636; EGC42184.1; -; Genomic_DNA.
DR EMBL; CP069103; QSS51398.1; -; Genomic_DNA.
DR AlphaFoldDB; F0U5U9; -.
DR STRING; 544711.F0U5U9; -.
DR VEuPathDB; FungiDB:I7I53_06710; -.
DR HOGENOM; CLU_029282_1_2_1; -.
DR OMA; IIVLWGQ; -.
DR Proteomes; UP000008142; Unassembled WGS sequence.
DR Proteomes; UP000663419; Chromosome 2.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR GO; GO:0051205; P:protein insertion into membrane; IEA:UniProt.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR PANTHER; PTHR12428:SF34; CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12428; OXA1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000008142};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
SQ SEQUENCE 366 AA; 41241 MW; 506B4718BA542E80 CRC64;
MSAPGYRLPI VALRTTHCGL NARLLRVSCP AQQCAVRLRA TAQQRRHFHP SRPTQMVSTS
IECAHDLLQI VHTYTGLPWV ASIPLTAMTA RVAFGLPFLN WSTSQRNKRL LANPAILAYT
RMKRKNIMDA AAKEQRFLPP QFVSRQSALE ASQFQKSLLK RHHLRLAPFA PFAPVLQLPF
WLAFMESIRS MSGWQPGLLA ILQQWFNPDG VKAQIPVEPS LSSQGALWFP DLMAADPLSV
LPVAISVLMF THITWGSKVS KMKDLPKLVS QGNLQGIFSW AIQRIFQAMS IWIAPTLLYS
EAPAALSIYW LSTTCVAIVQ SRLLKKYMPT PNVPKACVKR TIVRYVYERK PGTQELQKVA
RLGMMW
//
