ID   F0U8J5_AJEC8            Unreviewed;       259 AA.
AC   F0U8J5;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   SubName: Full=GDSL Lipase/Acylhydrolase {ECO:0000313|EMBL:EGC41745.1};
GN   ORFNames=HCEG_01107 {ECO:0000313|EMBL:EGC41745.1};
OS   Ajellomyces capsulatus (strain H88) (Darling's disease fungus) (Histoplasma
OS   capsulatum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Ajellomycetaceae; Histoplasma.
OX   NCBI_TaxID=544711 {ECO:0000313|Proteomes:UP000008142};
RN   [1] {ECO:0000313|Proteomes:UP000008142}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=H88 {ECO:0000313|Proteomes:UP000008142};
RA   Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., Young S.K.,
RA   Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA   Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A.,
RA   Gujja S., Heiman D., Hepburn T., Howarth C., Jen D., Larson L., Lewis B.,
RA   Mehta T., Park D., Pearson M., Roberts A., Saif S., Shea T., Shenoy N.,
RA   Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B.,
RA   McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G.,
RA   San-Blas G., Taylor J., Mendoza L., Galagan J., Nusbaum C., Birren B.;
RT   "Annotation of Ajellomyces capsulatus strain H88.";
RL   Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; DS990636; EGC41745.1; -; Genomic_DNA.
DR   AlphaFoldDB; F0U8J5; -.
DR   STRING; 544711.F0U8J5; -.
DR   HOGENOM; CLU_051989_0_0_1; -.
DR   OMA; HEPAWEK; -.
DR   Proteomes; UP000008142; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd01838; Isoamyl_acetate_hydrolase_like; 1.
DR   Gene3D; 3.40.50.1110; SGNH hydrolase; 1.
DR   InterPro; IPR045136; Iah1-like.
DR   InterPro; IPR013830; SGNH_hydro.
DR   InterPro; IPR036514; SGNH_hydro_sf.
DR   PANTHER; PTHR14209; ISOAMYL ACETATE-HYDROLYZING ESTERASE 1; 1.
DR   PANTHER; PTHR14209:SF19; ISOAMYL ACETATE-HYDROLYZING ESTERASE 1 HOMOLOG; 1.
DR   Pfam; PF13472; Lipase_GDSL_2; 1.
DR   SUPFAM; SSF52266; SGNH hydrolase; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EGC41745.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008142}.
FT   DOMAIN          25..221
FT                   /note="SGNH hydrolase-type esterase"
FT                   /evidence="ECO:0000259|Pfam:PF13472"
FT   REGION          158..177
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        158..175
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   259 AA;  28198 MW;  77953084FAC286E0 CRC64;
     MLIKHTVIPE ASSSPPYVEY EQFIIFGDSI TQGSCDQGRG FAFSPALQSG GFTLSLNYIR
     RFDIINRGFS GYTSQQALAI FPSFFPPVQK AKVRLMIVFF GANDAVLPGF EQHVPLPTYE
     ANLRKILTHP LIKEHKETNL LLLTPPPVDE YQFSAADTDT DMGTDTGTAT PSGTPEPASV
     AVMRKASQTK KYADACRQVG KALNVPVADI WTAFMTAAGW VEGQPLPGSR DAPANKKLQA
     LLSDGMCMSS NHEKLPLLT
//