ID F0VQV4_NEOCL Unreviewed; 544 AA.
AC F0VQV4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Nucleolar protein 56 {ECO:0000256|ARBA:ARBA00040742};
GN ORFNames=BN1204_065270 {ECO:0000313|EMBL:CEL70855.1}, NCLIV_065270
GN {ECO:0000313|EMBL:CBZ56101.1};
OS Neospora caninum (strain Liverpool).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC Eucoccidiorida; Eimeriorina; Sarcocystidae; Neospora.
OX NCBI_TaxID=572307 {ECO:0000313|EMBL:CBZ56101.1, ECO:0000313|Proteomes:UP000007494};
RN [1] {ECO:0000313|EMBL:CBZ56101.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CBZ56101.1};
RA Aslett M.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBZ56101.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CBZ56101.1};
RA Reid A.J., Sohal A., Harris D., Quail M., Sanders M., Berriman M.,
RA Wastling J.M., Pain A.;
RT "Comparative genomics and transcriptomics of Neospora caninum and
RT Toxoplasma gondii.";
RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000007494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Liverpool {ECO:0000313|Proteomes:UP000007494};
RX PubMed=22457617; DOI=10.1371/journal.ppat.1002567;
RA Reid A.J., Vermont S.J., Cotton J.A., Harris D., Hill-Cawthorne G.A.,
RA Konen-Waisman S., Latham S.M., Mourier T., Norton R., Quail M.A.,
RA Sanders M., Shanmugam D., Sohal A., Wasmuth J.D., Brunk B., Grigg M.E.,
RA Howard J.C., Parkinson J., Roos D.S., Trees A.J., Berriman M., Pain A.,
RA Wastling J.M.;
RT "Comparative genomics of the apicomplexan parasites Toxoplasma gondii and
RT Neospora caninum: Coccidia differing in host range and transmission
RT strategy.";
RL PLoS Pathog. 8:e1002567-e1002567(2012).
RN [4] {ECO:0000313|EMBL:CEL70855.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Liverpool {ECO:0000313|EMBL:CEL70855.1};
RX PubMed=25875305; DOI=10.1371/journal.pone.0124473;
RA Ramaprasad A., Mourier T., Naeem R., Malas T.B., Moussa E., Panigrahi A.,
RA Vermont S.J., Otto T.D., Wastling J., Pain A.;
RT "Comprehensive Evaluation of Toxoplasma gondii VEG and Neospora caninum LIV
RT Genomes with Tachyzoite Stage Transcriptome and Proteome Defines Novel
RT Transcript Features.";
RL PLoS ONE 10:e0124473-e0124473(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
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DR EMBL; FR823393; CBZ56101.1; -; Genomic_DNA.
DR EMBL; LN714487; CEL70855.1; -; Genomic_DNA.
DR RefSeq; XP_003886127.1; XM_003886078.1.
DR AlphaFoldDB; F0VQV4; -.
DR GeneID; 13445324; -.
DR VEuPathDB; ToxoDB:NCLIV_065270; -.
DR eggNOG; KOG2573; Eukaryota.
DR InParanoid; F0VQV4; -.
DR OrthoDB; 5489581at2759; -.
DR Proteomes; UP000007494; Chromosome XII.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF0; NUCLEOLAR PROTEIN 56; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007494}.
FT DOMAIN 312..441
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 465..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..497
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..544
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 60331 MW; E45F14A61D5105B5 CRC64;
MAVNEIFLLF ESAPGLLLAR VKGWDQIAQD TDAVQEACLD FGRFKQVVEA IAFHPFSDAE
EAMEVQLAIT NGTSCASLVN FLNFNLPSSL KKKKGADTVD GSAARAKSQA AVGVCDPALG
KSLADAGFQI VFNSNIQELH RGCRQHMKKL AKQLGELPIE KFQVGLGHSY SRSKMQEDPR
KQDKPIMQSI ALLDSLDKNI NAFAMKLKEW YGWHFPELVK IVGDAEAYCR VLKVVQMKEQ
FDAQAQGEEL LEACGGSEEI RDEVVAATKH SMGQEIGEAD FVNIIRFADQ VLRLCEQRRN
LQDYLSTKMD FVSPNLKAVV GEVLAARLIS HAGALVNLAK YPASTIQILG AEKALFRALK
SKNGRTPKYG LLFHSSFIGR VQKQQHRGRM SRYLASKCAL AARIDAFADE ESPESADGVR
SNVYGVKLRE QLEERLKYLA DGIVPRKNLD VMREAASELQ TQATAAAAEK KKKKKRKHEE
KEETNPMMDV EQESGEKKKK KKKKHAKPAE DGEDVDGEEA AAPAENMGTE KKKKKKKAHV
DAEL
//
