ID F0W8P7_9STRA Unreviewed; 979 AA.
AC F0W8P7;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Eukaryotic translation initiation factor 5B {ECO:0000256|ARBA:ARBA00013824};
DE AltName: Full=Translation initiation factor IF-2 {ECO:0000256|ARBA:ARBA00032478};
GN Name=AlNc14C36G3173 {ECO:0000313|EMBL:CCA17504.1};
GN ORFNames=ALNC14_036470 {ECO:0000313|EMBL:CCA17504.1};
OS Albugo laibachii Nc14.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Albuginales; Albuginaceae; Albugo.
OX NCBI_TaxID=890382 {ECO:0000313|EMBL:CCA17504.1};
RN [1] {ECO:0000313|EMBL:CCA17504.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21750662; DOI=10.1371/journal.pbio.1001094;
RA Kemen E., Gardiner A., Schultz-Larsen T., Kemen A.C., Balmuth A.L.,
RA Robert-Seilaniantz A., Bailey K., Holub E., Studholme D.J., Maclean D.,
RA Jones J.D.;
RT "Gene gain and loss during evolution of obligate parasitism in the white
RT rust pathogen of Arabidopsis thaliana.";
RL PLoS Biol. 9:e1001094-e1001094(2011).
RN [2] {ECO:0000313|EMBL:CCA17504.1}
RP NUCLEOTIDE SEQUENCE.
RA MacLean D.;
RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC {ECO:0000256|ARBA:ARBA00007733}.
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DR EMBL; FR824081; CCA17504.1; -; Genomic_DNA.
DR AlphaFoldDB; F0W8P7; -.
DR EnsemblProtists; CCA17504; CCA17504; ALNC14_036470.
DR HOGENOM; CLU_002656_2_0_1; -.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR CDD; cd03703; aeIF5B_II; 1.
DR CDD; cd16266; IF2_aeIF5B_IV; 1.
DR CDD; cd01887; IF2_eIF5B; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR InterPro; IPR029459; EFTU-type.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR015760; TIF_IF2.
DR InterPro; IPR023115; TIF_IF2_dom3.
DR InterPro; IPR036925; TIF_IF2_dom3_sf.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43381:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 5B; 1.
DR PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF14578; GTP_EFTU_D4; 1.
DR Pfam; PF11987; IF-2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 389..607
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 1..160
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..311
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 347..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 15..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 129..160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..270
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 271..286
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 979 AA; 109775 MW; 2B3750242851D4F3 CRC64;
MAPKKGKKTK RPAGNEANKN ATTDNDLDTL LNEFTPSPDV NNDAHEKAAN EADTEAPKSS
QNTADETEAA AAAFLKSMGV DAQAASSEKK DKKKKKPKKK AAASEESHPK SNEKKPPSAA
AKLLLERQEA IRAQQERIEK ERLEQERILR EEEEKRLEEE RRLEEIKKKK REAKAAKIER
QKKEGTYMTK AQKQKAAKAQ AALEAMQHSN NVVVGNNEEK KKVVYSNRKK GKAVVDQTKT
DSEGKEKVDA QAETVTVEEA EPKENEEAPN EAEAPDAWDN EDWESSEIIA SLEDKLQLNG
SADGSERKDD EVEDLLVVEQ RKEKEILRLQ GIALLKRQQE LKEVQERQAE EEHIRSKAQQ
EADRKKREAA DRRRVREEKA LANVSADDLR SPICCIMGHV DTGKTKLLDN IRRTKVQDGE
AGGITQQIGA TFFPVEAIKQ RTERLAKTMK LEYRLPGLLV IDTPGHESFT NLRSRGTSLC
DIAILVVDIM HGLEPQTLES LRLLRQKKAP FIVALNKIDR CYGWKVMADM PIQEALKHQN
EHVIREFEDR TKEIIVEFAK QKLNAEIYWK NNDLAHTVSL IPTSAISGEG VPDLLMMLTK
LSQDRMAKSL AYVDILQCTV LEVKVLEGLG TTIDTILVNG KLNEGDTIVV CTLDGPVVTH
IRSLLTPHPM KEIRVKGEYV HHSTMKAAMG IKICANGLEK AVAGTQIHVV GPDDDVEELK
DSVMSDLTGI LDSVKATKRG VMVQASTLGA LEALLEFLRT CDPPIPVACV NIGPVHKKDV
MRASVQLEHQ PEYATVLAFD VKVHHDATEL AQELGVRIFT ADIIYHLFDQ FTAYMDNFRS
TRREEVADIA VFPCVLKILP NCVFNKKDPI ILGVDVEEGV LKIGTPLVVP NAGMLFVGKV
SSIEREHKEV DRAKKGMSVA VRIENESNVT YGRHFDHKHR LFSRLTRQSI DALKENFRDD
LAKEDWQLVI KLKKVFDII
//
