ID F0X7S7_GROCL Unreviewed; 485 AA.
AC F0X7S7;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Negative regulator of DNA transposition protein {ECO:0000313|EMBL:EFX06425.1};
GN ORFNames=CMQ_6746 {ECO:0000313|EMBL:EFX06425.1};
OS Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus)
OS (Graphiocladiella clavigera).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Leptographium.
OX NCBI_TaxID=655863 {ECO:0000313|Proteomes:UP000007796};
RN [1] {ECO:0000313|EMBL:EFX06425.1, ECO:0000313|Proteomes:UP000007796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=kw1407 / UAMH 11150 {ECO:0000313|Proteomes:UP000007796};
RX PubMed=21262841; DOI=10.1073/pnas.1011289108;
RA DiGuistini S., Wang Y., Liao N.Y., Taylor G., Tanguay P., Feau N.,
RA Henrissat B., Chan S.K., Hesse-Orce U., Alamouti S.M., Tsui C.K.M.,
RA Docking R.T., Levasseur A., Haridas S., Robertson G., Birol I., Holt R.A.,
RA Marra M.A., Hamelin R.C., Hirst M., Jones S.J.M., Bohlmann J., Breuil C.;
RT "Genome and transcriptome analyses of the mountain pine beetle-fungal
RT symbiont Grosmannia clavigera, a lodgepole pine pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:2504-2509(2011).
CC -!- FUNCTION: Histones H3 and H4 chaperone involved in the nucleosome
CC formation and heterochromatin silencing. Required for the deposition of
CC H3K56ac-carrying H3-H4 complex onto newly-replicated DNA. Plays a role
CC in the transcriptional regulation of the cell-cycle dependent histone
CC genes by creating a repressive structure at the core histone gene
CC promoter. {ECO:0000256|ARBA:ARBA00037550}.
CC -!- SUBUNIT: Interacts with histones H3 and H4.
CC {ECO:0000256|ARBA:ARBA00038654}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC -!- SIMILARITY: Belongs to the RTT106 family.
CC {ECO:0000256|ARBA:ARBA00006159}.
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DR EMBL; GL629729; EFX06425.1; -; Genomic_DNA.
DR RefSeq; XP_014175907.1; XM_014320432.1.
DR AlphaFoldDB; F0X7S7; -.
DR STRING; 655863.F0X7S7; -.
DR GeneID; 25980213; -.
DR eggNOG; ENOG502R9PE; Eukaryota.
DR HOGENOM; CLU_033828_0_0_1; -.
DR InParanoid; F0X7S7; -.
DR OrthoDB; 1359279at2759; -.
DR Proteomes; UP000007796; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR013719; RTT106/SPT16-like_middle_dom.
DR PANTHER; PTHR45849; FACT COMPLEX SUBUNIT SSRP1; 1.
DR PANTHER; PTHR45849:SF3; HISTONE CHAPERONE RTT106; 1.
DR Pfam; PF08512; Rttp106-like_middle; 1.
DR SMART; SM01287; Rtt106; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007796}.
FT DOMAIN 267..361
FT /note="Histone chaperone RTT106/FACT complex subunit SPT16-
FT like middle"
FT /evidence="ECO:0000259|SMART:SM01287"
FT REGION 64..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 357..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..378
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 379..397
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..435
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..485
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 485 AA; 51904 MW; 934CA19EEEAE7FF3 CRC64;
MATGLDTERL RLAFETRPDL VTGIQKAADS PARVALFNSI ASFVCDRLQG DDEPAVKRRR
VQANAAAASN THTNGGLPGR PATGADGGGV SAAGLATAAA AETPILEIKD ISLSMPQRKK
LDLCFTQHYL YARAAGTTAP VQGIVYAWTD IEHVFCVPVP DKAQVQHSYV LLPRGQALAS
LSKTTTTPNG TAGLPEPLVF TVPAAAPKPG SVGGTAAGEA ATVADAYNTL LHWALEGRLP
SSSQIVRTDA KVFHSMARQA YRPSEKAVHV RAFRGSKDGF LFFLPTGILW GFKKPLLFLP
LDRVEAVSYT NVLQRTFNVV VEVDVGGGRT EEVEFGMLDQ EDYGSIDEAY VRRHGLQDRS
MAERRKAKRE LAENAKDGDG DGDEGEAEAE DEAEGGGTET TDGVKQEGTA ARPKTEQELQ
DEEDEMEEDY DPGSDDDSGG SGSSDGSVDE DEDDGDGDEE DEDEDMEDGE EEEEEGFDVV
GKAEE
//
