ID F0X8L3_GROCL Unreviewed; 843 AA.
AC F0X8L3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=Elongation factor 2 {ECO:0000256|ARBA:ARBA00017891};
GN ORFNames=CMQ_3520 {ECO:0000313|EMBL:EFX05451.1};
OS Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus)
OS (Graphiocladiella clavigera).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Leptographium.
OX NCBI_TaxID=655863 {ECO:0000313|Proteomes:UP000007796};
RN [1] {ECO:0000313|EMBL:EFX05451.1, ECO:0000313|Proteomes:UP000007796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=kw1407 / UAMH 11150 {ECO:0000313|Proteomes:UP000007796};
RX PubMed=21262841; DOI=10.1073/pnas.1011289108;
RA DiGuistini S., Wang Y., Liao N.Y., Taylor G., Tanguay P., Feau N.,
RA Henrissat B., Chan S.K., Hesse-Orce U., Alamouti S.M., Tsui C.K.M.,
RA Docking R.T., Levasseur A., Haridas S., Robertson G., Birol I., Holt R.A.,
RA Marra M.A., Hamelin R.C., Hirst M., Jones S.J.M., Bohlmann J., Breuil C.;
RT "Genome and transcriptome analyses of the mountain pine beetle-fungal
RT symbiont Grosmannia clavigera, a lodgepole pine pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:2504-2509(2011).
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DR EMBL; GL629735; EFX05451.1; -; Genomic_DNA.
DR RefSeq; XP_014174933.1; XM_014319458.1.
DR AlphaFoldDB; F0X8L3; -.
DR STRING; 655863.F0X8L3; -.
DR GeneID; 25976630; -.
DR eggNOG; KOG0465; Eukaryota.
DR HOGENOM; CLU_002794_4_1_1; -.
DR InParanoid; F0X8L3; -.
DR OrthoDB; 148165at2759; -.
DR Proteomes; UP000007796; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd03713; EFG_mtEFG_C; 1.
DR Gene3D; 3.30.230.10; -; 2.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR035649; EFG_V.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF1; RIBOSOME-RELEASING FACTOR 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EFX05451.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:EFX05451.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007796}.
FT DOMAIN 35..326
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 742..763
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 747..763
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 843 AA; 91898 MW; 41398881D73CD5DC CRC64;
MLLLSLAGVQ KTSISLRFVR AAHSSGPAYY DAKIEDIRNV GIIAHVDAGK TTTTERMLYY
SGVTRHLGNV DHGDTITDFL PLERQRGITI QSAAISFNWP PRQHLAEGVN AKTINLIDTP
GHQDFRFEVD RCLPVLDGAV CIIDAVKGVE AHTERVWSSA QRYGVPRIVY VNKLDRDGAS
FKRAVLDVAS RLNAYPLVCQ LPLWEKEDSF VGVVDVIRRR AMKWTASGTC TLVPEAAVRS
NERLWEELET ARTRLVERLC EDDDELVEAF AEVGADLPAD MIVDSIRRVV RNSGGLVVPV
FAGSSLRNIG VEPLLDAIVD YLPSPQQAPD VKVQVGGSET MTLGEALRAH DDGRAKTAKT
TKTTQQHHPS VGAVASVFKV VNDPALFPGT HGMLTFVRVY HGALHKNAQV WNANLGLFEK
PFQIVQVAAA QVGEIPYLSP GQIGAVTGLK AARTGDTLHI LPSHSRGMPV ARLRTMTIRP
AEMRPAVAFV SAEAYGTSET KRLEEALGKL SREDPSLRWS KDEKLDTFVL SGMGTLHLDI
AIDRLKTTYK VNAAFSDVQV DYKECLTAAT ARHHSVYDRV IANKAGRAGC TATIAPLKGG
GEREEAGEME YRRTIDRDGN VYEIRFTTAS GRLPFDADEL SRQLFSGAYG AMARGPRRGS
PLHGCRVVLE FDVEADYGGA GTEGHVVNAA LQAVRGALRE AHSHGTVAVL EPVMLVHIGC
PDDSAGAIQR DITGSRGGFV HEVREGGSGR PSAEAEKGES TESAEKTINL GQVYAPADPY
ESVQSLRATK RGVTRMLEIV ARVPLKEMLS YDSRLRSMTG GWHSLTMVLD SFERVMGSRE
KNV
//
