ID F0XA60_GROCL Unreviewed; 870 AA.
AC F0XA60;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Carnitine acetyl transferase {ECO:0000313|EMBL:EFX06125.1};
GN ORFNames=CMQ_4194 {ECO:0000313|EMBL:EFX06125.1};
OS Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus)
OS (Graphiocladiella clavigera).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Leptographium.
OX NCBI_TaxID=655863 {ECO:0000313|Proteomes:UP000007796};
RN [1] {ECO:0000313|EMBL:EFX06125.1, ECO:0000313|Proteomes:UP000007796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=kw1407 / UAMH 11150 {ECO:0000313|Proteomes:UP000007796};
RX PubMed=21262841; DOI=10.1073/pnas.1011289108;
RA DiGuistini S., Wang Y., Liao N.Y., Taylor G., Tanguay P., Feau N.,
RA Henrissat B., Chan S.K., Hesse-Orce U., Alamouti S.M., Tsui C.K.M.,
RA Docking R.T., Levasseur A., Haridas S., Robertson G., Birol I., Holt R.A.,
RA Marra M.A., Hamelin R.C., Hirst M., Jones S.J.M., Bohlmann J., Breuil C.;
RT "Genome and transcriptome analyses of the mountain pine beetle-fungal
RT symbiont Grosmannia clavigera, a lodgepole pine pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:2504-2509(2011).
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR EMBL; GL629735; EFX06125.1; -; Genomic_DNA.
DR RefSeq; XP_014175607.1; XM_014320132.1.
DR AlphaFoldDB; F0XA60; -.
DR STRING; 655863.F0XA60; -.
DR GeneID; 25977378; -.
DR eggNOG; KOG3719; Eukaryota.
DR HOGENOM; CLU_013513_4_0_1; -.
DR InParanoid; F0XA60; -.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000007796; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 1.10.275.20; Choline/Carnitine o-acyltransferase; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR042572; Carn_acyl_trans_N.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF29; MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED; 1.
DR Pfam; PF00755; Carn_acyltransf; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00439; ACYLTRANSF_C_1; 1.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000007796};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EFX06125.1};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 85..616
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT DOMAIN 668..743
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT REGION 612..671
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 632..671
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 391
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 870 AA; 96493 MW; AE7D7A45B95363DE CRC64;
MSTQVRTFTA PKPLGESLSS AASIATNLQS PYIPRSVPTY PDIPRYNAGG SRAQIKPSSM
SAYVNDQAGG NGGITFAHQD SLPKLPIPEL ESTLQKYLTV LRPLQTTREH AETRIAVEEF
LRQDGPELQE KLKKYAEGRT SYIEQFWYDS YLNYDNPVVL NLNPFFLLED DPTPARNNQV
NRAASLIVSS LMFVRAVRKE ELPPDTIRGT PLDMYQYSRL FGTARVPTDN GCQIEQDPES
KHIVVMCHGQ FYWFDVLDDN SDLIMTERDV ALNLQTIIGD ATQTPIQEAA KGALGVLSTE
NRKVWSGLRD VLTREEGSNN ADCLSIVDSA LFVVCLDYTE PASAAAVCQN MLCGTSDIEK
GVQIGTCTNR WYDKLQIIVC KNGSAGINFE HTGVDGHTVL RFASDVYTDT ILRFARSING
QAPSMWKSTS PDPARRDPES FGDVTATPHK LEWDMVPELT IAVRFAESRL ADLIEQNEFQ
CLDFGAYGKN FITSMGFSPD AFVQMAFQAA YYGLYGRVEC TYEPAMTKVY LHGRTEAIRS
VTEESVHFVQ TFWADNQAEL KVEALRRACQ RHVTSTRECS KAQGCDRHLY ALFCLWQRLA
DDELFSNTGT GTSSADYGSS FGSERGFSPV PEENGSVNSH GNGHVNGNGS SSNETPARAR
GDSTGSRQSG QHMPAIFLDS GWDKLNTTIL STSNCGNPSL RQFGFGPVSG DGFGIGYIIK
DDGISICVSS KHRQTKRFVD TLESYLLEMR RVLRITSRRL GSISSKQMSR AREIDNMRPR
PPTRVKSRGR LITGGDVIKS MSRLGTESPT TDSMAMSEDD ELGGYGFFDA GMLLQALKAR
NEGYDLGEPK PSERASRRRD IGKKLRLIDY
//
