ID F0XDE3_GROCL Unreviewed; 522 AA.
AC F0XDE3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Pseudouridylate synthase 3 {ECO:0000313|EMBL:EFX04135.1};
GN ORFNames=CMQ_1063 {ECO:0000313|EMBL:EFX04135.1};
OS Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus)
OS (Graphiocladiella clavigera).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Ophiostomatales; Ophiostomataceae; Leptographium.
OX NCBI_TaxID=655863 {ECO:0000313|Proteomes:UP000007796};
RN [1] {ECO:0000313|EMBL:EFX04135.1, ECO:0000313|Proteomes:UP000007796}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=kw1407 / UAMH 11150 {ECO:0000313|Proteomes:UP000007796};
RX PubMed=21262841; DOI=10.1073/pnas.1011289108;
RA DiGuistini S., Wang Y., Liao N.Y., Taylor G., Tanguay P., Feau N.,
RA Henrissat B., Chan S.K., Hesse-Orce U., Alamouti S.M., Tsui C.K.M.,
RA Docking R.T., Levasseur A., Haridas S., Robertson G., Birol I., Holt R.A.,
RA Marra M.A., Hamelin R.C., Hirst M., Jones S.J.M., Bohlmann J., Breuil C.;
RT "Genome and transcriptome analyses of the mountain pine beetle-fungal
RT symbiont Grosmannia clavigera, a lodgepole pine pathogen.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:2504-2509(2011).
CC -!- SIMILARITY: Belongs to the tRNA pseudouridine synthase TruA family.
CC {ECO:0000256|ARBA:ARBA00009375}.
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DR EMBL; GL629765; EFX04135.1; -; Genomic_DNA.
DR RefSeq; XP_014173617.1; XM_014318142.1.
DR AlphaFoldDB; F0XDE3; -.
DR STRING; 655863.F0XDE3; -.
DR GeneID; 25973900; -.
DR eggNOG; KOG2554; Eukaryota.
DR HOGENOM; CLU_014673_2_3_1; -.
DR InParanoid; F0XDE3; -.
DR OrthoDB; 167554at2759; -.
DR Proteomes; UP000007796; Unassembled WGS sequence.
DR GO; GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0001522; P:pseudouridine synthesis; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.660; Pseudouridine synthase I, catalytic domain, C-terminal subdomain; 1.
DR Gene3D; 3.30.70.580; Pseudouridine synthase I, catalytic domain, N-terminal subdomain; 1.
DR HAMAP; MF_00171; TruA; 1.
DR InterPro; IPR020103; PsdUridine_synth_cat_dom_sf.
DR InterPro; IPR001406; PsdUridine_synth_TruA.
DR InterPro; IPR020097; PsdUridine_synth_TruA_a/b_dom.
DR InterPro; IPR020095; PsdUridine_synth_TruA_C.
DR InterPro; IPR020094; TruA/RsuA/RluB/E/F_N.
DR NCBIfam; TIGR00071; hisT_truA; 1.
DR PANTHER; PTHR11142; PSEUDOURIDYLATE SYNTHASE; 1.
DR PANTHER; PTHR11142:SF5; TRNA PSEUDOURIDINE(38_39) SYNTHASE; 1.
DR Pfam; PF01416; PseudoU_synth_1; 1.
DR SUPFAM; SSF55120; Pseudouridine synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000007796};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 224..349
FT /note="Pseudouridine synthase I TruA alpha/beta"
FT /evidence="ECO:0000259|Pfam:PF01416"
FT REGION 23..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 522 AA; 57460 MW; 3A12469CDC898ED9 CRC64;
MADYSRWTKE ALVRRVQQLE QDVAKARQRP AAADTTTSTA TATPKAKKSM DPSRYASRFI
ALKLAYLGKR YGGFEYQPSG ALPTIEEELW KALTKACLVF PAPGASADEV DLVRCEYSKC
GRTDRGVSAF GQVVALRVRS NKRAVYAKVL NRLLPPDIRV LAWCATPPAD FSARFSCRER
QYRYFFTQPA YFTEDGSRPG PTSSAGSASQ PPDGWLDIDA MRDAATRFVG LHDFRNFCKV
DPSKQITNFE RRIFAAGITE VADVHSSLRC LSSSASSVSF PRVYSFDVRG SAFLWHQIRH
MVAVLFLVGQ GREPADVVSQ LLGVAAQPGR PNYPMADETP LVLWDCIFPP LGLPGVDDSV
DSPTAGNWSD SLQWLYVGHA DNDDAGEPPS RMFIDGLWRG WRTAKMDEIL ANRLLDLVTA
GPVTVAESSH TTTSHTTTRI ACPGPPGNKS HVFEGGDGPR LAGIYVPLLK RPRLAAPDDV
NDRYARQKGF DSADAMRQTG NWRAAIKARK EEAKADEAMT AE
//
