ID F0Y0W2_AURAN Unreviewed; 352 AA.
AC F0Y0W2;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Geranylgeranyl pyrophosphate synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AURANDRAFT_52464 {ECO:0000313|EMBL:EGB11284.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB11284.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; GL833122; EGB11284.1; -; Genomic_DNA.
DR RefSeq; XP_009033669.1; XM_009035421.1.
DR AlphaFoldDB; F0Y0W2; -.
DR EnsemblProtists; EGB11284; EGB11284; AURANDRAFT_52464.
DR GeneID; 20222199; -.
DR KEGG; aaf:AURANDRAFT_52464; -.
DR eggNOG; KOG0776; Eukaryota.
DR InParanoid; F0Y0W2; -.
DR OMA; EGMIGGQ; -.
DR OrthoDB; 687190at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR43281; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR43281:SF1; FARNESYL DIPHOSPHATE SYNTHASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SFLD; SFLDG01017; Polyprenyl_Transferase_Like; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Isoprene biosynthesis {ECO:0000256|ARBA:ARBA00023229};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000002729};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..352
FT /note="Geranylgeranyl pyrophosphate synthase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003261251"
SQ SEQUENCE 352 AA; 37406 MW; B5012A65D6959BDD CRC64;
MARYLPVRAC LFASLFGVAT SLVGPAPAFR HARSPVVRSV LAEPSVASPA ELAKDFDLKA
YFAQKVAAVE KALDESLTCT TPETKIIVES MRYSLLAGGK RVRPVMCIAA CEMFGGTEAM
AMPTAVAIEM IHTMSLIHDD LPAMDNDDLR RGMPTNHVIY GDDVAILAGD ALLSTSFEHC
AVGSTAEGIP AERIVETIRR LGEAVGAVGL AGGQVMDLEC EAKSGVSLEE LTWIHTHKTA
KLLEVSVAAG AVLAGAAKDD VRQCETYAND IGIAFQVADD ILDVTATSEM LGKTAGKDED
TDKTTYPKLM GLDGARAEAD RLYSEAIDSL APYGEKAVPL IAIAKYIVER QN
//
