ID F0Y5K8_AURAN Unreviewed; 449 AA.
AC F0Y5K8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=O-acetylhomoserine aminocarboxypropyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AURANDRAFT_24591 {ECO:0000313|EMBL:EGB09513.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB09513.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933,
CC ECO:0000256|RuleBase:RU362118};
CC -!- SIMILARITY: Belongs to the trans-sulfuration enzymes family.
CC {ECO:0000256|ARBA:ARBA00009077, ECO:0000256|RuleBase:RU362118}.
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DR EMBL; GL833125; EGB09513.1; -; Genomic_DNA.
DR RefSeq; XP_009035577.1; XM_009037329.1.
DR AlphaFoldDB; F0Y5K8; -.
DR EnsemblProtists; EGB09513; EGB09513; AURANDRAFT_24591.
DR GeneID; 20219933; -.
DR KEGG; aaf:AURANDRAFT_24591; -.
DR eggNOG; KOG0053; Eukaryota.
DR InParanoid; F0Y5K8; -.
DR OMA; THFRMDA; -.
DR OrthoDB; 6018at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0016765; F:transferase activity, transferring alkyl or aryl (other than methyl) groups; IEA:InterPro.
DR GO; GO:0019346; P:transsulfuration; IEA:InterPro.
DR CDD; cd00614; CGS_like; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR000277; Cys/Met-Metab_PyrdxlP-dep_enz.
DR InterPro; IPR006235; OAc-hSer/O-AcSer_sulfhydrylase.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR NCBIfam; TIGR01326; OAH_OAS_sulfhy; 1.
DR PANTHER; PTHR43797; HOMOCYSTEINE/CYSTEINE SYNTHASE; 1.
DR PANTHER; PTHR43797:SF2; HOMOCYSTEINE_CYSTEINE SYNTHASE; 1.
DR Pfam; PF01053; Cys_Met_Meta_PP; 1.
DR PIRSF; PIRSF001434; CGS; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR PROSITE; PS00868; CYS_MET_METAB_PP; 1.
PE 3: Inferred from homology;
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898,
KW ECO:0000256|PIRSR:PIRSR001434-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000002729}.
FT MOD_RES 222
FT /note="N6-(pyridoxal phosphate)lysine"
FT /evidence="ECO:0000256|PIRSR:PIRSR001434-2"
SQ SEQUENCE 449 AA; 48279 MW; 0C605D619B6A0C59 CRC64;
MADDATLGFD TLCLHGAYKP DTSVTYGLGQ GAPRGVPLHR TTPYQFVDTQ HAADLFALAK
LGNIYTRLMN PTTHVLESRY AMLEGGHPLS GLCVASGTNA VFYSLINLAR QGDNIVSSRA
LYGGTYTQFE EILPQFGIEV RFVDAEDPEN FAKATDAKTR AWFCESCSNP ALEICDLEAI
TTLAHAQNGT GLPVVVDTTF STPYLCKPFE FGVDVIVSSL TKWVGGHGTA IGGIIVDSGR
FKWGAGNHPL FDEPDMSYGG DAGLRWGHDL PEGLAPLAYK LRALTVPLRN LGGCISPDNS
WMVLQGIETL SLRMERHCEN AMTVAKHLKM NPKIAWVRYP GLVDDPQYQK AKKYLKGKGG
SMVVFGIKAP DGKVAGSKFI DSLDLISHVA NVGDARTLAI HPATTTHSQM NAAAQLGAGV
KPEMVRLSVG LETAKDIIAD IDQALAKAV
//
