ID F0Y6D6_AURAN Unreviewed; 549 AA.
AC F0Y6D6;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=HRDC domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AURANDRAFT_63530 {ECO:0000313|EMBL:EGB08974.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB08974.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL833126; EGB08974.1; -; Genomic_DNA.
DR RefSeq; XP_009036103.1; XM_009037855.1.
DR AlphaFoldDB; F0Y6D6; -.
DR EnsemblProtists; EGB08974; EGB08974; AURANDRAFT_63530.
DR GeneID; 20224380; -.
DR KEGG; aaf:AURANDRAFT_63530; -.
DR eggNOG; KOG2206; Eukaryota.
DR InParanoid; F0Y6D6; -.
DR OrthoDB; 2880475at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR GO; GO:0000467; P:exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IEA:InterPro.
DR Gene3D; 1.10.150.80; HRDC domain; 1.
DR Gene3D; 3.30.1370.50; R3H-like domain; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR010997; HRDC-like_sf.
DR InterPro; IPR002121; HRDC_dom.
DR InterPro; IPR044876; HRDC_dom_sf.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR045092; Rrp6-like.
DR PANTHER; PTHR12124; POLYMYOSITIS/SCLERODERMA AUTOANTIGEN-RELATED; 1.
DR PANTHER; PTHR12124:SF68; PROTEIN RRP6-LIKE 3; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF00570; HRDC; 1.
DR SMART; SM00474; 35EXOc; 1.
DR SUPFAM; SSF47819; HRDC-like; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50967; HRDC; 1.
DR PROSITE; PS51061; R3H; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002729}.
FT DOMAIN 31..111
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT DOMAIN 463..547
FT /note="HRDC"
FT /evidence="ECO:0000259|PROSITE:PS50967"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..423
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..418
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 59144 MW; 86275CEFF299FDB9 CRC64;
MGRPYHNNNN RGKGGRGRGR GRGRGRGPQN REQEAAVRRV LAHLAAGTLE HVKLVGEDAA
VCNVVNGLVA FSPALGGRER SIAHGVAGDL GLYHWSEGDG EARRAYASRD PRPDPGGGRA
AAAVAAVARA FLDKPQASWP PLANDLRRVS EGAAARWERR RGDDWETTDE RPVHPHADRV
AALLAAPPTR ASPAAPVARR AAAPRPVNFV DSTEALAALA RALEGVDVFG VDLEAHAEHS
YESIACLVQI STADVDYVVD ALALRFELRA LAPAFADPNI RKVFHACQGV DIPRLQRDFG
IFVVNVFDTQ EAARCAARVL GAPLGLVALY ASAGVISTAR RDELESLKRA YQNCDWRSRP
LSPAQLEYAV CDARHLVDLE AYLNRELRHF DPLRDYGLPP GGAARDAPRP PPPPGPREAA
GDEEADMVAS AYCKSQRATL CLWRAPRSPR LQAARDKQFA ALARDAAPRF SALVAWRDAE
ARRLDEGPHA VCPSAALAAF AKRWPTTLRG LLLAFDPLPP LVATDAFGVR ASLLACLAAL
AENQVNPYL
//
