ID F0Y9K2_AURAN Unreviewed; 1795 AA.
AC F0Y9K2;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE RecName: Full=FAD-binding PCMH-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AURANDRAFT_71657 {ECO:0000313|EMBL:EGB08328.1};
OS Aureococcus anophagefferens (Harmful bloom alga).
OC Eukaryota; Sar; Stramenopiles; Ochrophyta; Pelagophyceae; Pelagomonadales;
OC Aureococcus.
OX NCBI_TaxID=44056 {ECO:0000313|Proteomes:UP000002729};
RN [1] {ECO:0000313|EMBL:EGB08328.1, ECO:0000313|Proteomes:UP000002729}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCMP 1984 {ECO:0000313|Proteomes:UP000002729};
RX PubMed=21368207; DOI=10.1073/pnas.1016106108;
RA Gobler C.J., Berry D.L., Dyhrman S.T., Wilhelm S.W., Salamov A.,
RA Lobanov A.V., Zhang Y., Collier J.L., Wurch L.L., Kustka A.B., Dill B.D.,
RA Shah M., VerBerkmoes N.C., Kuo A., Terry A., Pangilinan J., Lindquist E.A.,
RA Lucas S., Paulsen I.T., Hattenrath-Lehmann T.K., Talmage S.C., Walker E.A.,
RA Koch F., Burson A.M., Marcoval M.A., Tang Y.Z., Lecleir G.R., Coyne K.J.,
RA Berg G.M., Bertrand E.M., Saito M.A., Gladyshev V.N., Grigoriev I.V.;
RT "Niche of harmful alga Aureococcus anophagefferens revealed through
RT ecogenomics.";
RL Proc. Natl. Acad. Sci. U.S.A. 108:4352-4357(2011).
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DR EMBL; GL833128; EGB08328.1; -; Genomic_DNA.
DR RefSeq; XP_009037051.1; XM_009038803.1.
DR EnsemblProtists; EGB08328; EGB08328; AURANDRAFT_71657.
DR GeneID; 20228327; -.
DR KEGG; aaf:AURANDRAFT_71657; -.
DR eggNOG; KOG0430; Eukaryota.
DR InParanoid; F0Y9K2; -.
DR OMA; PVTQCAG; -.
DR OrthoDB; 3715804at2759; -.
DR Proteomes; UP000002729; Unassembled WGS sequence.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR GO; GO:0005506; F:iron ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.790; -; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR Gene3D; 3.30.465.10; -; 1.
DR Gene3D; 1.10.150.120; [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.90.1170.50; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; 1.
DR Gene3D; 3.30.365.10; Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain; 4.
DR Gene3D; 3.30.390.50; CO dehydrogenase flavoprotein, C-terminal domain; 1.
DR Gene3D; 1.20.120.1740; Sodium ion translocating NADH-quinone reductase subunit C-like; 1.
DR InterPro; IPR002888; 2Fe-2S-bd.
DR InterPro; IPR036884; 2Fe-2S-bd_dom_sf.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR006058; 2Fe2S_fd_BS.
DR InterPro; IPR036856; Ald_Oxase/Xan_DH_a/b_sf.
DR InterPro; IPR016208; Ald_Oxase/xanthine_DH-like.
DR InterPro; IPR008274; AldOxase/xan_DH_MoCoBD1.
DR InterPro; IPR046867; AldOxase/xan_DH_MoCoBD2.
DR InterPro; IPR037165; AldOxase/xan_DH_Mopterin-bd_sf.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR InterPro; IPR005107; CO_DH_flav_C.
DR InterPro; IPR036683; CO_DH_flav_C_dom_sf.
DR InterPro; IPR016166; FAD-bd_PCMH.
DR InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR002346; Mopterin_DH_FAD-bd.
DR InterPro; IPR040933; PSII_Pbs31.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR11908:SF132; ALDEHYDE OXIDASE 1-RELATED; 1.
DR PANTHER; PTHR11908; XANTHINE DEHYDROGENASE; 1.
DR Pfam; PF03450; CO_deh_flav_C; 1.
DR Pfam; PF00941; FAD_binding_5; 1.
DR Pfam; PF00111; Fer2; 1.
DR Pfam; PF01799; Fer2_2; 1.
DR Pfam; PF02738; MoCoBD_1; 1.
DR Pfam; PF20256; MoCoBD_2; 1.
DR Pfam; PF18240; PSII_Pbs31; 1.
DR SMART; SM01092; CO_deh_flav_C; 1.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR SUPFAM; SSF55447; CO dehydrogenase flavoprotein C-terminal domain-like; 1.
DR SUPFAM; SSF47741; CO dehydrogenase ISP C-domain like; 1.
DR SUPFAM; SSF54665; CO dehydrogenase molybdoprotein N-domain-like; 1.
DR SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR SUPFAM; SSF56003; Molybdenum cofactor-binding domain; 1.
DR PROSITE; PS00197; 2FE2S_FER_1; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS51387; FAD_PCMH; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714};
KW Iron {ECO:0000256|ARBA:ARBA00022714};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022714};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000002729}.
FT DOMAIN 213..291
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
FT DOMAIN 396..593
FT /note="FAD-binding PCMH-type"
FT /evidence="ECO:0000259|PROSITE:PS51387"
FT REGION 1591..1615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1773..1795
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1795 AA; 187419 MW; EA9C460058351485 CRC64;
MKLSFLLFGG AAALAPQPVK LDRRQAMKTV AGTFAAAVAA PQIASADGAV SAATVARSRG
IYGGRIADLK DAVEKGDFAA VLAEKNAFDL FNSGAYAQKS AITKAQKAIA VTETKNIMEA
IASKNANQLK TSYAAYMKNA AIDTKPVDVS TGQGYSNDYD WKRAFPASTP MYLYLLALVV
LSWVLLRLRR RAEPVEARSE DPVKSPPAED PPSTVVLTIN GAVHCVENPS PSLTLLAYLR
DRCGLTAAKV GCGEGGCGAC TVVEHNTDAI NACLRLLCQC DGSVITTAEG LGSSRNGFGD
IQKAIADGNG SQCGYCTPGW TTAVAALRAR GPRSRGDLQK KLDGNICRCT GYRPILEALE
GLPDVEDAAP CRDVTTGRAC GRACGAPPSR GLSVADDARR LSYVEPTSLP RLYALLDAGL
GYGETVLVGG ATAAIGVAKY YDDCLGAPWA GGLPPLEDAQ LVATKSVPEL TKLAAADDGL
AAGGAVTIDA LSAALRGGLD VAWNAAAAHL DRVANTQVRN SATWAGNLAL AARADGFPSD
VAVALACLGA ELSVSRRDGK TKRRLQKLAV VDVLTGWRAG DVVVELFVPR SPAGTTARCD
KVAARHANAH AYVNAGLSVR VASGVVASAR LFFGGVAPRT KLFRATAAEA ALAGKPVADA
DAFQAAVAAL RAQLPTDDAY ATDCAVQLLY KACLLAQPSL PPRVANALRS LAAHRPPSSG
ARDVAGASDG RYAPACAPRV KLAARLQASG EARYAADEPR ACNEVSVAFA FAKRSGTVTA
VDVSGAARVL GAVAVYSRDD ALRDLVATES LALDDADDLL LWGVGDDVFV GCRVALCVGT
SDLAALAMAR AVRCATDGGA GGAAALTSAE LKAALAAHFS DDGSGKGRKL GLRRGALRVV
DDHVVLKTTS STTTDDRVVL KTTSSTKTDD RVVLKTTSST KTVSGAFATP LQKHFHMETH
SARCVPGEGS RLLLTASTQD PTLTQTVTAS LLGLRAADVV VACRRAGGGF GGKLTLHLPA
ATSVALVAAK LGVPARYHAD RRDDMAMTGG REATACDYEV SFDAATGALA SYAATFAVEG
GHATQDAVGD LSMAVQWSDN CYDSGRHDAK GKVLKTRAPR SSSMRSPGVI QSQCCRELAI
VRVAHETRRP VHEVQELNFY KVGQKFPYGS KPLGSPTFNY TIPELYAALK PKLLARLDAV
DQFNEANAWR KRGVHVMPTK YIMAMDFWKV PALVNVYGDG SVQVAHGGCE LGQGIHTKVA
AVAAYALGCD LSLVTVADTS TDKTPNSVAT GGSGTSESCC GATLKACATL KKRLAPYVAK
HAKWADAVAA ALADAVELSA TGWNDLRTSE SGDDPDYATY GLALAEVEVD CLSGEVEVRE
VDVRMDQGSS LNSDVDVGQV EGAIVMALGF YLTEHCAVDA SGKQSGDGTW EYKPPMVADV
PLDLRVSMLA RTPNPSAVAV LGSKASGEPP MQLAASVFFA LRAAVAAFRR DALGDAAWFD
LPVPASPKAI RAALGRLDDA GLVFAYSMAT DDRFDSLSFC AFHFEMWGRT GDAARVPSPS
RALSTNRTAR ATAETESMAA LAAMAGKLGL DMDDLNDSDR PPPGPPKDPN EPVLAPVMGK
SSVEVIEGSD EIRPEGWWHP KGASEQGQKS DAPVLAPEKL AAEAASAYVE TVPFDTFALS
DEGKKVVLYF GLPGAKANLG KDAVAASFRT QALEVTARVG SKRYRFHESI IYEHIVPAKG
KVKVKSDHVV VTMFKVHAAC PWDTISVNRK AVGPVRTSPP DHGRPTVVTA SGDAA
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