ID F0Z4Y4_9CLOT Unreviewed; 788 AA.
AC F0Z4Y4;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE SubName: Full=Anaerobic ribonucleoside-triphosphate reductase {ECO:0000313|EMBL:EGB90866.1};
GN ORFNames=HMPREF0240_04187 {ECO:0000313|EMBL:EGB90866.1};
OS Clostridium sp. D5.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=556261 {ECO:0000313|EMBL:EGB90866.1, ECO:0000313|Proteomes:UP000003978};
RN [1] {ECO:0000313|EMBL:EGB90866.1, ECO:0000313|Proteomes:UP000003978}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=D5 {ECO:0000313|EMBL:EGB90866.1,
RC ECO:0000313|Proteomes:UP000003978};
RG The Broad Institute Genome Sequencing Platform;
RA Ward D., Earl A., Feldgarden M., Gevers D., Young S., Zeng Q., Koehrsen M.,
RA Alvarado L., Berlin A.M., Borenstein D., Chapman S.B., Chen Z., Engels R.,
RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., Heilman E.R.,
RA Heiman D.I., Hepburn T.A., Howarth C., Jen D., Larson L., Mehta T.,
RA Park D., Pearson M., Richards J., Roberts A., Saif S., Shea T.D.,
RA Shenoy N., Sisk P., Stolte C., Sykes S.N., Walk T., White J., Yandava C.,
RA Sibley C.D., White A.P., Crowley S., Surette M.G., Strauss J.C.,
RA Ambrose C.E., Allen-Vercoe E., Haas B., Nusbaum C., Birren B.;
RT "The Genome Sequence of Clostridium sp. D5.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GL870821; EGB90866.1; -; Genomic_DNA.
DR RefSeq; WP_009005460.1; NZ_GL870821.1.
DR AlphaFoldDB; F0Z4Y4; -.
DR eggNOG; COG0526; Bacteria.
DR eggNOG; COG1328; Bacteria.
DR HOGENOM; CLU_002707_0_2_9; -.
DR OrthoDB; 9804622at2; -.
DR Proteomes; UP000003978; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008998; F:ribonucleoside-triphosphate reductase activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd01675; RNR_III; 1.
DR Gene3D; 3.20.70.20; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR005144; ATP-cone_dom.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR012833; NrdD.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR NCBIfam; TIGR02487; NrdD; 1.
DR PANTHER; PTHR21075; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR PANTHER; PTHR21075:SF0; ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE; 1.
DR Pfam; PF03477; ATP-cone; 1.
DR Pfam; PF00462; Glutaredoxin; 1.
DR Pfam; PF13597; NRDD; 1.
DR SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51161; ATP_CONE; 1.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00492};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00492}; Reference proteome {ECO:0000313|Proteomes:UP000003978}.
FT DOMAIN 2..95
FT /note="ATP-cone"
FT /evidence="ECO:0000259|PROSITE:PS51161"
SQ SEQUENCE 788 AA; 88870 MW; 65AFBE0EE91C7CC9 CRC64;
MYQVTKRDGK IADFDLAKIC EAIRKAFEAR ERQYNQDIID LLALKVTADF EPKIKKGLVS
VEDVQDSVES VLIKAGYADV AKGYILYRKQ REKIRNLNST LLDYKEIVDS YVKITDWRVK
ENSTVTYSVG GLILSNSGAI TANYWLSEIY DDEVGKAHKN ADIHIHDLSM LTGYCAGWSL
KQLIQDGLGG ITGRITSAPA KHLSVLCNQM VNFLGIMQNE WAGAQAFSSF DTYLAPFVKI
DNLTYPEVKK CIESFIYGVN IPSRWGTQAP FSNITLDWTV PGDLAHLPAI VGGIEQDFTY
GDCKEEMDMI NKAFIETMIE GDADGRGFQY PIPTYSITND FDWSDTENNR LLFEMTAKYG
TPYFSNYINS DMEPSDVRSM CCRLRLDLRE LRKKSGGFFG SGESTGSIGV VTINMPRIAY
LADNEEEFYK HLDKMMDISA SSLHTKRVVI SKLMDEGLYP YTKRYLGSFE NHFSTIGLIG
MNEAGLNAKW IGKDMTSAET QQFTKDVLNH MRERLSDYQE MYGELYNLEA TPAESTTYRL
AKHDVEQFPD IITAAEGDGT PYYTNSSHLP VGYTEDVFEA LDIQDELQTL YTSGTVFHTF
LGEKLPGWKS AASLVKKIAE NYKLPYYTMS PTYSICKNHG YISGELYKCP HCGEETEVYS
RITGYYRPVK NWNDGKTQEF KDRKVYDISN SNMSIKTHEA KKAAEEAEIP AGEMKTLLFT
TKTCPNCKIA TSSLEKANIA YEIVDAEENE ELVKKYGVMQ APTLVVIGEK GVQKMANASN
IKAYAEEH
//
