ID   F0ZK53_DICPU            Unreviewed;       943 AA.
AC   F0ZK53;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   24-JAN-2024, entry version 46.
DE   RecName: Full=EGF-like domain-containing protein {ECO:0000259|PROSITE:PS50026};
GN   ORFNames=DICPUDRAFT_151960 {ECO:0000313|EMBL:EGC35670.1};
OS   Dictyostelium purpureum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC35670.1, ECO:0000313|Proteomes:UP000001064};
RN   [1] {ECO:0000313|Proteomes:UP000001064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX   PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA   Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA   Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA   Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA   Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA   Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA   Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT   "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT   Dictyostelium purpureum.";
RL   Genome Biol. 12:R20.1-R20.23(2011).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR   EMBL; GL871052; EGC35670.1; -; Genomic_DNA.
DR   RefSeq; XP_003287803.1; XM_003287755.1.
DR   AlphaFoldDB; F0ZK53; -.
DR   STRING; 5786.F0ZK53; -.
DR   EnsemblProtists; EGC35670; EGC35670; DICPUDRAFT_151960.
DR   GeneID; 10500987; -.
DR   KEGG; dpp:DICPUDRAFT_151960; -.
DR   eggNOG; KOG1225; Eukaryota.
DR   InParanoid; F0ZK53; -.
DR   OMA; NIANGIC; -.
DR   OrthoDB; 18546at2759; -.
DR   Proteomes; UP000001064; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.10.25.10; Laminin; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR013111; EGF_extracell.
DR   InterPro; IPR002909; IPT_dom.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   PANTHER; PTHR24032:SF14; EGF-LIKE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR24032; EGF-LIKE DOMAIN-CONTAINING PROTEIN-RELATED-RELATED; 1.
DR   Pfam; PF07974; EGF_2; 1.
DR   Pfam; PF01833; TIG; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS00022; EGF_1; 1.
DR   PROSITE; PS50026; EGF_3; 1.
PE   4: Predicted;
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        7..23
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        898..922
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          596..629
FT                   /note="EGF-like"
FT                   /evidence="ECO:0000259|PROSITE:PS50026"
FT   DISULFID        600..610
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT   DISULFID        619..628
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ   SEQUENCE   943 AA;  103895 MW;  A119E2EC81315248 CRC64;
     MKISTSIIFF IISVIFIILL PNNNNKNLVQ STKYEDLSCL SNFLSQVFSF PPEETVVCSN
     SIIDANGFSY YPMCNSDDTE LIKLSIKMIS FTPKKITYNL LNCFTNLEEL TLKNFLIAEN
     ALGTDDDSKG VATKIFLDEC SFDSGYITSS DQLNLSFDFV SDYPDKLSDP KNKIKKLSIN
     GTLVASDPNG YSIQPGLESL VLIGQSIDFN IASKFPFNTP FPDSLKEISV NSLGLTSLPT
     VFPEGIEIIG IDNNDGISSE GIFTLPDFSN YKNLKKVSLV GNKISGSIPE SYCLFEPVLT
     DNNLSGSLPK CFSCFIDQFP TNFNGNLLTN IAICESGSIV PSLEYDSSSK QLILTGSTLG
     LQGPFINNVK KSFQVVVPQS KYTFSWDTEA YGPPPDKLSV QIGSNNYTLA TKILDPKIYV
     VRKGGNTFTI EGNNFSYEKT DIKIHIAGIE ASITHIDYYT IVFNFIGKTL PFDKQVPATI
     QNTKLSKIFS FSVNTIDNIT TLVTQCNSDC GIPLGLGRIC NSNIGKCQCD IYYAGETCNL
     PNQFLSSISS IPETGGKVEI SFANCTVGAG TGTQSVTVFQ NGITWTRQNF FHFTQTTFKC
     PKDCSNNGQC NTATGQCKCN LEWAGFDCNS KANIDGGTAT TGGSTETTPI EIPKSNTTVN
     ESTGSTAIGN QQTVYEIKIL SLAEINVLGE IVNLYNLTNK WSSSSSSNKN IYSFTQTIEH
     SSTITYTVEE IKTERDYPFA GLDLTLDKDS IKITVSIKNY PFSSVLNTLQ LRLESTVGEI
     EDQSNNECNN KGTEIDTNQI DKDQLLNYVT ISKNKKTLYG RFINRVLSNE RETFITTEVI
     SKNMFSGTSE NNIKNKDTFI IGLNLPHCSS ECLIDPDFSV LVSSDYKQCE SKRGRASWVL
     PVAIIVPCVG LVLIIIIGAI IIKKNRINFL MAKRRVYKLK SFN
//