ID   F0ZL83_DICPU            Unreviewed;       770 AA.
AC   F0ZL83;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   24-JAN-2024, entry version 54.
DE   RecName: Full=Atg6 BARA domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DICPUDRAFT_97940 {ECO:0000313|EMBL:EGC35303.1};
OS   Dictyostelium purpureum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC35303.1, ECO:0000313|Proteomes:UP000001064};
RN   [1] {ECO:0000313|Proteomes:UP000001064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX   PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA   Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA   Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA   Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA   Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA   Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA   Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT   "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT   Dictyostelium purpureum.";
RL   Genome Biol. 12:R20.1-R20.23(2011).
CC   -!- SIMILARITY: Belongs to the beclin family.
CC       {ECO:0000256|ARBA:ARBA00005965}.
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DR   EMBL; GL871064; EGC35303.1; -; Genomic_DNA.
DR   RefSeq; XP_003288170.1; XM_003288122.1.
DR   AlphaFoldDB; F0ZL83; -.
DR   STRING; 5786.F0ZL83; -.
DR   EnsemblProtists; EGC35303; EGC35303; DICPUDRAFT_97940.
DR   GeneID; 10501598; -.
DR   KEGG; dpp:DICPUDRAFT_97940; -.
DR   eggNOG; KOG2751; Eukaryota.
DR   InParanoid; F0ZL83; -.
DR   OMA; DAFHLWH; -.
DR   OrthoDB; 11439at2759; -.
DR   Proteomes; UP000001064; Unassembled WGS sequence.
DR   GO; GO:0000407; C:phagophore assembly site; IBA:GO_Central.
DR   GO; GO:0034271; C:phosphatidylinositol 3-kinase complex, class III, type I; IBA:GO_Central.
DR   GO; GO:0034272; C:phosphatidylinositol 3-kinase complex, class III, type II; IBA:GO_Central.
DR   GO; GO:0000045; P:autophagosome assembly; IBA:GO_Central.
DR   GO; GO:0006995; P:cellular response to nitrogen starvation; IBA:GO_Central.
DR   GO; GO:0045324; P:late endosome to vacuole transport; IBA:GO_Central.
DR   Gene3D; 6.10.250.3110; -; 1.
DR   Gene3D; 1.10.418.40; Autophagy protein 6/Beclin 1; 1.
DR   InterPro; IPR007243; Atg6/Beclin.
DR   InterPro; IPR038274; Atg6/Beclin_C_sf.
DR   InterPro; IPR041691; Atg6/beclin_CC.
DR   InterPro; IPR040455; Atg6_BARA.
DR   PANTHER; PTHR12768; BECLIN 1; 1.
DR   PANTHER; PTHR12768:SF4; BECLIN-1; 1.
DR   Pfam; PF04111; APG6; 1.
DR   Pfam; PF17675; APG6_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001064}.
FT   DOMAIN          425..552
FT                   /note="Atg6/beclin coiled-coil"
FT                   /evidence="ECO:0000259|Pfam:PF17675"
FT   DOMAIN          555..730
FT                   /note="Atg6 BARA"
FT                   /evidence="ECO:0000259|Pfam:PF04111"
FT   REGION          126..361
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          744..770
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          461..519
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   770 AA;  86568 MW;  A5F68352E0630FC5 CRC64;
     MDLYCQKCCK QLELDDSLLD IDTSIFFNQD LSSIAKQIEP FTFTLPKERE IEIFKQQKEQ
     QRELELAALQ SPSQQQKEQN SSKIFKVFSK KRDSQISASV PSSTNLSNST TIPTAAAATT
     TTVATNATPS NISNSPTSTP TSPIGVKVNA TNSDDKKAFK TFYPSTHSSN SEHSGGSPSS
     PSTFGSLSHH RISASLSSRS LQNNGIASSS PPKSSTTPTN NTISDNTGKT PPTSSSPSLS
     NSTSKSISSS PNRITSPIIN NRSSSNITSP KPSTPKQRPT TMTPNKINIT QVTSPQKPKL
     KYLRSSSKSL SMASLPNLPS DDLNNNNNNN NENNYLSQST IPIGSPIQTT PPLAGTTTSN
     SLPNNQLINN MNISVNNLNI STNSTISNSN NLNNSLAGNQ NNYLKYMKGS QLFKITTELI
     HYDLPLCLEC TKLTISEIED ETLMLDGEIS IYNTYLQRLE NQKTNEQIEQ INGELDELEC
     EEHNLRQFIQ DTYKEREDVE ILTNQLQEKR SQLKSLEDGY WSSFSELHYE AFKNQDEREQ
     TAVQIQWINE HLESLKQTNI LNDAFHLWHD GHFGTINSLR LGKLPSQPVE WNEINAAWGL
     TIFLLDNIAK KLKYKFKQYT LVPNGSCSRI EKRDDPSAAS YELFGSNDIS LGLLFWYRRF
     DSGMIAFLHC IKELVEFIVE KEPEFTIPYQ IEKDLINGTS IKMQFTNDDT WTKSLKYMLT
     NLKWILVWVT KYESQLSHNN YQKNQQKINQ SNQPQPQPPP QQQQNSVNKK
//