ID   F0ZNI6_DICPU            Unreviewed;      1260 AA.
AC   F0ZNI6;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 58.
DE   RecName: Full=Pleckstrin domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DICPUDRAFT_79745 {ECO:0000313|EMBL:EGC34493.1};
OS   Dictyostelium purpureum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC34493.1, ECO:0000313|Proteomes:UP000001064};
RN   [1] {ECO:0000313|Proteomes:UP000001064}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX   PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA   Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA   Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA   Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA   Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA   Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA   Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT   "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT   Dictyostelium purpureum.";
RL   Genome Biol. 12:R20.1-R20.23(2011).
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DR   EMBL; GL871095; EGC34493.1; -; Genomic_DNA.
DR   RefSeq; XP_003288982.1; XM_003288934.1.
DR   AlphaFoldDB; F0ZNI6; -.
DR   STRING; 5786.F0ZNI6; -.
DR   EnsemblProtists; EGC34493; EGC34493; DICPUDRAFT_79745.
DR   GeneID; 10499740; -.
DR   KEGG; dpp:DICPUDRAFT_79745; -.
DR   eggNOG; KOG0192; Eukaryota.
DR   InParanoid; F0ZNI6; -.
DR   OMA; FNTCINR; -.
DR   OrthoDB; 7608at2759; -.
DR   Proteomes; UP000001064; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004672; F:protein kinase activity; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   CDD; cd13999; STKc_MAP3K-like; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR23257:SF984; MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE; 1.
DR   PANTHER; PTHR23257; SERINE-THREONINE PROTEIN KINASE; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001064}.
FT   DOMAIN          39..164
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   DOMAIN          744..1079
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          264..344
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          790..820
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        267..344
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1260 AA;  141729 MW;  3053A2EFAFC0350D CRC64;
     MITNNNSNNN NNNNNNSSNN NNSNNSNSDN NNKDDKDEKI IHSGYLTKQG GNIQNWKIRW
     FVLKKGTLSY YISPINWESS KPRGVIYLTK RTEVKETLHR NRRYCFTVNP NYMLENQSIQ
     QSPALRSSAD SIRKYPNTTR VYLISAQTVF DQKKWIEMIK LAINNDELKS SLKKANQLEK
     VKDLVRRKES LPMHPSLLNR TIQTESINDN IRVQLSKKKF YFYHDNLTLP SLSYIETDIP
     LDLQEIHHQH LVILQQQKEE IKMKLQSLEQ KQSSSNNNSQ SSSNTTSAAN SNKVSPTTSP
     YSGSPLSSSP LSTSPTKKFT NMLSTSPPKS PNRPASPTLG NNESPFYGAP ITRLPLLSSS
     VVSGNSIGMV SNGTPVISSM NASIASSANA LNYKNNNTGD YSSSPSIAYN QLISVSNQVS
     HRHQPKIVVY HLVRDSFQIS NIGGCPFNFE ILSPFDQNYT INFIPSNGTV QKGESLTVLV
     ELMAYNHIEI DIYTTLHIIG GMEFTLYCRV ETDPYLPLFL KSCSGSLLSG ENKKRMEYFI
     RNHPTMIKSI QELAHTMIAE GRNIPPIQMA PNNSGWNILS NKSPHHHNLM LMNQMNNHSL
     SSSTSSSSSA ARVRLSKYVL NYQRHQKKTS REGKGPEAVK IYQLLTDKFL ISNSGSADAQ
     FRFNFPSRGK KNNQYNLTLV PTSGSIAKGE WFYIKSTLTV FVETEISEVI QLVINQKEIH
     YILVTVKCEN LHPGNKEIDV ENEIILQDRL GTGATGDIYK GLITQENLNR HVNIDLSELL
     SGQNHNNTGQ NWLIARNPSN DSIKNRNSSN GSNNSSNNNA SNTQIIVAVK KLHPLTEPSP
     EMIQDFYNEV RLLSMFNHPN IVKYVGGCTK IGNWSIVMEY VPGGNLMDVL SNPVLLIPYK
     LILRMALDVA KGLHYLHSLG ILHLDLKSPN LLVSSLSTNS KVNIKVADFN TCINRNRITG
     FFKPSVLLSK DSESDLKKDS KKGTTLWMAP EVIRGALYSE KCDVYSFGII MWEMVTRKLP
     YSHISFNCEV EDQVIKGLRP PIPMNCNKTY TDLMEECWDD DPEKRPQFDT IIHRLNKMVE
     NNNIQEQKAK ASVKGLRRTQ SNSALNVFGN NSDPNTIVNK FDSPPLILTQ DPNLLINLNN
     NNNNNNSNNN STTTTTTTTT TTTTTAYNNI KNNNNNNNNN KNSTISVSQF DGEFVHSKHK
     SKRFSFDGSS VHSSILTINN DSNLPFKFSP PSTPQGSFLQ LKKLDKELKQ NLENQKSIHL
//