ID F0ZQ37_DICPU Unreviewed; 1403 AA.
AC F0ZQ37;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DICPUDRAFT_98398 {ECO:0000313|EMBL:EGC33943.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC33943.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
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DR EMBL; GL871119; EGC33943.1; -; Genomic_DNA.
DR RefSeq; XP_003289525.1; XM_003289477.1.
DR STRING; 5786.F0ZQ37; -.
DR EnsemblProtists; EGC33943; EGC33943; DICPUDRAFT_98398.
DR GeneID; 10502639; -.
DR KEGG; dpp:DICPUDRAFT_98398; -.
DR eggNOG; KOG1815; Eukaryota.
DR InParanoid; F0ZQ37; -.
DR OMA; PWSEHGD; -.
DR OrthoDB; 12359at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:GO_Central.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR GO; GO:0000209; P:protein polyubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd22583; Rcat_RBR_ARI7-like; 1.
DR CDD; cd16773; RING-HC_RBR_TRIAD1; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR11685:SF422; RBR-TYPE E3 UBIQUITIN TRANSFERASE; 1.
DR Pfam; PF01485; IBR; 2.
DR SMART; SM00647; IBR; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 927..1143
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 931..975
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 154..207
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 630..684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 718..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 790..874
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 111..139
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 718..764
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 795..841
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..874
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1403 AA; 160584 MW; 7768E3BAFF38BDCF CRC64;
MGVHNSKEIR GNQYNDEQPQ QIEQQQQHHT NQIQQQQQQQ QRVLSDTAIH VKKRISLRKK
LKSISFSSSK SPIFSPNNSN FTNNNYSSTN NNINNINNIH REKENEDLGN DQDEINNTDD
ENLDYEYDEE GTSDEEEIID DTLDDTAFLP RIASKNKNDN NTVFSPSIIN NNDKNNNGSS
SSPSSSSSIV SPSILNQQTP VNNTTNYISS SSNSNWYSLE NAESYTITKE NDKNVCVISM
EDIIYILEEQ VSRASEILGL DLPSSSTILI HYKWNMETLL LNFIEKGDEV LFAEAGVFNP
TEKSQENIKI IDLLLPIGSY LKKGGEFLVN SSPSSINSAN LTPVSTTNNI IPNNNTPPSN
TNNENFNNTL NEIIMFPDSP QRIRSSLRPL RVRWDNNNNN NITNNNNIAN NYIPNIRART
HNHMNSITIN AWNLPSSSIS NINNTQYLNN LNKAIINSPP FQSSSQTTNM EINTNDDFEE
TIDDIYNKLN DISNSFESNH TFKELNEYRQ MELRASQEKE GEKKDQMCSS SINNFNSNLN
NINNNNNNLN NFNNINNNNN INSNKKIVPN NKLLDIKYDI SNPPPSPRPV RRLAFVKMLK
KDNNELITKQ QVQPKPFEYY INNRNVNNLE ISGDGNTNEN ENTQNNSKDE KTTTTTTTTT
TPTTTTTTTT TTTTTTSTTN NYSPYISSNL NPMSLSSDNS FLCTTEEIDK TNSTYTFNNE
ISSESGESET NFPTPPTTRL NNNSNENNIQ PNNNTGVNIN DNNSNEDDEY SEKDGADEEI
LNLDGAAIIN EDNQNESESE SESESESESE SESESESESE SESESESESE SESESESESE
SENENENKNI NNNITNNNYN DNNHNNNCNN INNNNINQNE NENVNNNNIE NNIIENIYYS
FNNENKSPKT EIETKTEEKN IGKENEEEIM CNVCLTETPK SNTFSLSCKH SYCLDCWDSY
LTTKIEEGPA CLFSRCIEPK CKLVLNILNF RKILNDKVYC RYLYIYIKSF IEHNQKTTWC
SNPQSCNMAI HYHGIDLPKI LNVTCSCNWR FCFHCGEEYH MPALCNQLDD WKILKNKEEG
QNAIWLSHNT KKCPKCKIHI EKNEGCMHMC CSSCRAEFCW LCKGPWSEHG DRTGGFFSCN
RYDPLKHDTP DLDKTFGTYA HHFQRYNYHQ NAKKYAMGKL KILELDESKL LKLPLNELHL
QIIQVGKQFI YEAMNLILEC RHTLKNTYVY GYYIKDNKER ELFEFLQEDL EKSTEHLCEI
VFDEITTYHR YIYKYPTAIS RLSSPSSFNP PINHSNSNLD FNTYDNHNYS SSLSSSTSSL
EEDNKQYSGL ELIQMFETQS FQHVQTYHKT TKKFLENLLS GISNGLLSDY GPPSNHSLKI
QNNSKKHKGS LSLFKRKITF PKI
//
