ID F0ZYQ8_DICPU Unreviewed; 1565 AA.
AC F0ZYQ8;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=IPT/TIG domain-containing protein {ECO:0000259|SMART:SM00429};
GN ORFNames=DICPUDRAFT_58027 {ECO:0000313|EMBL:EGC30921.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC30921.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
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DR EMBL; GL871290; EGC30921.1; -; Genomic_DNA.
DR RefSeq; XP_003292550.1; XM_003292502.1.
DR STRING; 5786.F0ZYQ8; -.
DR EnsemblProtists; EGC30921; EGC30921; DICPUDRAFT_58027.
DR GeneID; 10508426; -.
DR KEGG; dpp:DICPUDRAFT_58027; -.
DR eggNOG; KOG1840; Eukaryota.
DR eggNOG; KOG3602; Eukaryota.
DR InParanoid; F0ZYQ8; -.
DR OMA; YFRDPYY; -.
DR OrthoDB; 8116at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0080008; C:Cul4-RING E3 ubiquitin ligase complex; IBA:GO_Central.
DR CDD; cd00102; IPT; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR InterPro; IPR025139; DUF4062.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR19860; DDB1- AND CUL4-ASSOCIATED FACTOR 12-RELATED; 1.
DR PANTHER; PTHR19860:SF24; TPR REPEAT-CONTAINING PROTEIN DDB_G0287407; 1.
DR Pfam; PF13271; DUF4062; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF01833; TIG; 1.
DR Pfam; PF13424; TPR_12; 3.
DR SMART; SM00429; IPT; 1.
DR SMART; SM00028; TPR; 5.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS50005; TPR; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 130..218
FT /note="IPT/TIG"
FT /evidence="ECO:0000259|SMART:SM00429"
FT REPEAT 1083..1116
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 1211..1244
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 295..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1382..1402
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1540..1565
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1385..1401
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1565 AA; 179615 MW; 4C037657362D4FC1 CRC64;
MKNTFKDKYI YILSLDEIQR EKCKSFVIYK KGKLEKRFSK KVDIIITTLK TINENKFPIS
TAKKLETELV EYDSISKDVE RYSRKTNIKF ADQQPLPQSS SQITTLATTN NKIVKVNPNL
VQPQPAAVND PTITLIIPPS GPSYGGYQIS IYGISFAPGP SFRVRFGDNI FATNYEFHSN
SSVLCTVPYG INPSIGQVPV YASNDGKQFG YPIHFLFFDG NIHKIPTPKE QDGVVLRCQL
ENLKRAITNI SNMESILLKR LANLNDDRLD QLYITNHESG ASQLLEGHDG LMDDCSEYSS
RPSTNDDDDN DLSDDDSDED LISSNSSINR EEFAEREIRI FISSPFKDMK FDRDQIVKVV
IPKIRKLCIE RDIMISYVDL RWGVTSNQSE QSNSLSMCLK ELEKCNVLIG LFGERYGWSA
QEKSDPKTQQ LLVSTLDHAI NDFPWVNKFR DASMTEIEFR MLLNNPNSGK NGFFYFRDPY
YIEELPQIEK NNYVSEGPRS KEKLDKLKQE ITKNQQFKSS EYRRPTNLSD VLYEDLEKFI
DKKFPSGNCE LKGFEKERFL HSIFYKSLIK FYITNETYFM DIDTFITTSK KQVLLVQGDS
GIGKSSLMCN WLKQHKEQHP EDFSISHWVG ASPSSNKFTS TLIRVMHELK HLIEKDQKLS
SSGGASVFSS SASSSSWVPE IPDETLESEK ISHEFTLFIQ YIMSHPTMNG KRVIVLIDGL
DKMDQRDNSQ ELIWFPKIYP QGFKMIVSTT NSTRQAEILK KRNSSIINIQ PFSEPERKSM
VRLYLQKYAK KLTDQQEIQI AISKSTSNPR FLQLVLDDIL VFGDYEKLDT RVKTLYRAKN
TSNLYEIILD RIEKDYDPKG KGLVKEFLKY IWGSRRGIEI SMMTSLLNKK NIDPEEWSSL
LVLMENYISY SSGVITFLNN DIADAVERKY INNTRDVYLD LAQEYEVSQD LTERFIEEYP
YHLLKSENWE KLNSTLTNLF VFDKLYTPHH KVDLINYWNV LEKQTKPPRN AAERDDPIPY
KCSSEFQAVV SRSFIQASGL VISDLWYRVA SFMEEISQYD GSESFYTKCR ELYVNNSQNL
EAAKVDRAMG RMYLTKGQYE KSEAKFKAAL AIYTKERGEE DIEVAITLNL LGTLATNRNK
HEDAKKVLYQ AMNICENKYE SNSLLVADVA YSLGVVHFVE EARKLDVAEQ FFARALELTE
LKLGDNDVSY ARILTRLGSL YIEKDQFSDA ESCFKGSLKI YESNFGLSHS RVAQILRHMI
SLYEMQEEYK KAEQCATRAI DITKKIFGSN HQIVLSTQIR LAIILNTVKR KQEALQILFD
IKSIREKECG VEHKDYKHIL DVIKEIEKVP IPLPPPPPPP MFGTIPIPLP LSSQPPKPVV
KLGANGIPLP PPPPPPILPV NRPSLQSIMR NSVGKINQAQ PVAVNQAQPP SPRRQQQQQL
QQQQQQQVQQ IRQQNINQLQ QQQQQQLPQQ QMNRNIAPPQ QQQQMNRNIT PQQLQQNIQL
QEAYVGDQLA QFNINVLKKV AVNDRSGASA MVSNLIGKKK CSKPQPISQK SYMTESNDDM
GGLFD
//
