ID F1A2X3_DICPU Unreviewed; 363 AA.
AC F1A2X3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=OTU domain-containing protein {ECO:0000259|PROSITE:PS50802};
GN ORFNames=DICPUDRAFT_84523 {ECO:0000313|EMBL:EGC29451.1};
OS Dictyostelium purpureum (Slime mold).
OC Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC Dictyosteliaceae; Dictyostelium.
OX NCBI_TaxID=5786 {ECO:0000313|EMBL:EGC29451.1, ECO:0000313|Proteomes:UP000001064};
RN [1] {ECO:0000313|Proteomes:UP000001064}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QSDP1 {ECO:0000313|Proteomes:UP000001064};
RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., Dalin E.,
RA Tu H., Huang E., Barry K., Lindquist E., Shapiro H., Bruce D., Schmutz J.,
RA Salamov A., Fey P., Gaudet P., Anjard C., Babu M.M., Basu S.,
RA Bushmanova Y., van der Wel H., Katoh-Kurasawa M., Dinh C., Coutinho P.M.,
RA Saito T., Elias M., Schaap P., Kay R.R., Henrissat B., Eichinger L.,
RA Rivero F., Putnam N.H., West C.M., Loomis W.F., Chisholm R.L., Shaulsky G.,
RA Strassmann J.E., Queller D.C., Kuspa A., Grigoriev I.V.;
RT "Comparative genomics of the social amoebae Dictyostelium discoideum and
RT Dictyostelium purpureum.";
RL Genome Biol. 12:R20.1-R20.23(2011).
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DR EMBL; GL871430; EGC29451.1; -; Genomic_DNA.
DR RefSeq; XP_003294017.1; XM_003293969.1.
DR AlphaFoldDB; F1A2X3; -.
DR EnsemblProtists; EGC29451; EGC29451; DICPUDRAFT_84523.
DR GeneID; 10505340; -.
DR KEGG; dpp:DICPUDRAFT_84523; -.
DR eggNOG; KOG2605; Eukaryota.
DR InParanoid; F1A2X3; -.
DR OrthoDB; 7641at2759; -.
DR Proteomes; UP000001064; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IBA:GO_Central.
DR GO; GO:0019538; P:protein metabolic process; IEA:UniProt.
DR CDD; cd22758; OTU_232R-like; 1.
DR Gene3D; 3.90.70.80; -; 1.
DR InterPro; IPR003323; OTU_dom.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR PANTHER; PTHR12419; OTU DOMAIN CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12419:SF11; OTU DOMAIN-CONTAINING PROTEIN DDB_G0284757; 1.
DR Pfam; PF02338; OTU; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS50802; OTU; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001064};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 228..361
FT /note="OTU"
FT /evidence="ECO:0000259|PROSITE:PS50802"
FT REGION 56..109
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 124..147
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 127..141
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 363 AA; 42250 MW; 7265A52BA1381ABD CRC64;
MDNFLYMYFY LIFVATISLC LSFGIGLFIF KKKIVKEGVY ENVDCQVSKD EIWGNQVPQQ
QEQHQQHQPQ QHQQHQYQQY QQHQQYQHHQ QSQQNQQHQQ PKLNSSTPNY KSLLKSIRDY
VVEDEEQQPQ PKTQPQPKPK HTASTPGYKL LLKKINDYVV EDEPQPQQQP QKRQPPHQLQ
KNTSQKIKDL LKALVNSFGK LCLQPPQLSE VEKAHKRLNK RLELYQLMER REIPGDGNCQ
MHALSDQLYG NLNHSRAIRN IIVTWLRKNR GFSLSNGATL SEFVTTTSWD QYCNNMSKNG
TWGDHLTLVA AAEIFRINIS IISSVETQSN FVTEITPSKK SDHGILLSHF AEFHYGSLCQ
LVN
//
