ID F1DG74_9EURY Unreviewed; 416 AA.
AC F1DG74;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Translation elongation factor-1 alpha {ECO:0000313|EMBL:ADX78276.1};
DE Flags: Fragment;
OS Pyrococcus sp. LMO-A35.
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Pyrococcus.
OX NCBI_TaxID=984982 {ECO:0000313|EMBL:ADX78276.1};
RN [1] {ECO:0000313|EMBL:ADX78276.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=LMO-A35 {ECO:0000313|EMBL:ADX78276.1};
RA Liu L.;
RT "Diversity of Thermococcales Isolates from Guaymas Basin Hydrothermal
RT Vents.";
RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC subfamily. {ECO:0000256|ARBA:ARBA00007249}.
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DR EMBL; HQ834267; ADX78276.1; -; Genomic_DNA.
DR AlphaFoldDB; F1DG74; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd01883; EF1_alpha; 1.
DR CDD; cd03693; EF1_alpha_II; 1.
DR CDD; cd03705; EF1_alpha_III; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 2.
DR HAMAP; MF_00118_A; EF_Tu_A; 1.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR031157; G_TR_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR InterPro; IPR004539; Transl_elong_EF1A_euk/arc.
DR InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR NCBIfam; TIGR00483; EF-1_alpha; 1.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR23115:SF170; ELONGATION FACTOR 1-ALPHA 2; 1.
DR PANTHER; PTHR23115; TRANSLATION FACTOR; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR Pfam; PF03143; GTP_EFTU_D3; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SUPFAM; SSF50465; EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS00301; G_TR_1; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 3: Inferred from homology;
KW Elongation factor {ECO:0000256|ARBA:ARBA00022768,
KW ECO:0000313|EMBL:ADX78276.1}; GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT DOMAIN 1..211
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADX78276.1"
FT NON_TER 416
FT /evidence="ECO:0000313|EMBL:ADX78276.1"
SQ SEQUENCE 416 AA; 46154 MW; 1697BB5B6F7C5C91 CRC64;
HVNIVFIGHV DHGKSTTIGR LLYDTGNIPE TIIKKFEEMG EKGKSFKFAW VMDRLKEERE
RGITIDVAHT KFETPHRYIT IIDAPGHRDF VKNMITGASQ ADAAVLVVAA TDGVMPQTKE
HAFLARTLGI KHIIVAINKM DMVNYDQKVF EKVKAQVEKL LKMLGYKDFP VIPISAWEGD
NVVKKSDKMP WYNGPTLIEA LDKIPEPEKP IDKPLRIPIQ DVYSIKGVGT VPVGRVETGK
LKVGDVVIFE PASTIFHKPI QGEVKSIEMH HEPLQEALPG DNIGFNVRGV SKNDIKRGDV
AGHANNPPTV VRTKDTFKAQ IIVLNHPTAI TVGYSPVLHA HTAQVPVRFE QLLAKLDPRT
GNIVEENPQF IKTGDSAIVI LRPMKPVVLE PVKEIPQLGR FAIRDMGMTV AAGMVI
//
