ID F1KJB3_9HIV1 Unreviewed; 240 AA.
AC F1KJB3;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Pol protein {ECO:0000313|EMBL:ADY92328.1};
DE Flags: Fragment;
GN Name=pol {ECO:0000313|EMBL:ADY92328.1};
OS Human immunodeficiency virus 1.
OC Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
OC Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus.
OX NCBI_TaxID=11676 {ECO:0000313|EMBL:ADY92328.1};
OH NCBI_TaxID=9606; Homo sapiens (Human).
RN [1] {ECO:0000313|EMBL:ADY92328.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=47clone51 {ECO:0000313|EMBL:ADY92328.1};
RX PubMed=21241214; DOI=10.1089/aid.2010.0346;
RA Persaud D., Bedri A., Ziemniak C., Moorthy A., Gudetta B., Abashawl A.,
RA Mengistu Y., Omer S.B., Isehak A., Kumbi S., Adamu R., Lulseged S.,
RA Ashworth R., Hassen E., Ruff And The Ethiopian Swen Study Team A.;
RT "Slower Clearance of Nevirapine Resistant Virus in Infants Failing Extended
RT Nevirapine Prophylaxis for Prevention of Mother-to-Child HIV
RT Transmission.";
RL AIDS Res. Hum. Retroviruses 27:823-829(2011).
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DR EMBL; JF336125; ADY92328.1; -; Genomic_DNA.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR41694; ENDOGENOUS RETROVIRUS GROUP K MEMBER POL PROTEIN; 1.
DR PANTHER; PTHR41694:SF3; RNA-DIRECTED DNA POLYMERASE-RELATED; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW RNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022918};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Viral release from host cell {ECO:0000256|ARBA:ARBA00023113};
KW Virion maturation {ECO:0000256|ARBA:ARBA00023113}.
FT DOMAIN 41..231
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ADY92328.1"
FT NON_TER 240
FT /evidence="ECO:0000313|EMBL:ADY92328.1"
SQ SEQUENCE 240 AA; 27869 MW; 41FDC9CC76EC098F CRC64;
PIETVPVKLK PGMDGPKVKQ WPLTKEKIEA LTAICEEMEK EGKITKIGPE NPYNTPVFAI
KKKDSTKWRK LVDFREPNKR TQDFWEVQLG IPHPAGLKKK KSVTVLDVGD AYFSVPLDEN
FRKYTAFTIP SINNETPGIR YQYNVLPQGW KGSPSIFQCS MTKILEPFRA QNPEIVIYQY
MDDLYVGSDL EIKQHRAKIE ELREHLLKWG FTTPDKKHQK GPPFLWMGYE LHPDKWTVQP
//
