ID F1KQ43_ASCSU Unreviewed; 2092 AA.
AC F1KQ43;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Teneurin-2 {ECO:0000313|EMBL:ADY39997.1};
DE Flags: Fragment;
OS Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6253 {ECO:0000313|EMBL:ADY39997.1};
RN [1] {ECO:0000313|EMBL:ADY39997.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21685128; DOI=10.1101/gr.121426.111;
RA Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA Davis R.E.;
RT "Deep small RNA sequencing from the nematode Ascaris reveals conservation,
RT functional diversification, and novel developmental profiles.";
RL Genome Res. 21:1462-1477(2011).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JI164061; ADY39997.1; -; mRNA.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 2.160.20.10; Single-stranded right-handed beta-helix, Pectin lyase-like; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR012334; Pectin_lyas_fold.
DR InterPro; IPR011050; Pectin_lyase_fold/virulence.
DR PANTHER; PTHR24033; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07974; EGF_2; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00181; EGF; 7.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF51126; Pectin lyase-like; 1.
DR PROSITE; PS00022; EGF_1; 3.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 3.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 651..685
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 719..753
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 787..821
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 675..684
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 743..752
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 811..820
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 2092
FT /evidence="ECO:0000313|EMBL:ADY39997.1"
SQ SEQUENCE 2092 AA; 232138 MW; 3F85330ABE516393 CRC64;
MKLRDISQSD LHVLRGNFTR NKGTTLSITR LAAGSNVQIK DNRFWYNQLL KTSIPSSVLE
VETLEGNKTS WSRLQINGNT FLRNTMENIV QVGSAERQAI PSIARLSFSS NVLLSNLAID
VVALAISNAN VTLNRFENVQ AQCELRTGIR SGNALVLATN NFWGTDKEIE VSERICDSRW
DDSLMPALIT PILSKPPPVV DHFLLVASTN YVRPSFSQIM NETLFIEEGE TSVFEEGAML
LFKPGKGIVI SGTLHLSGQE NNPIIIRSTG GEPWSGIVVK PRGTLVVNHC ILEGALSALV
IDSAFVHLNA LQIIRPLRMG IEITRESSED IDLGYSSIIS SLGSAIRIAR RDTPIAVRNA
AIKENAEMGL DFEDPSGNIT IRNITIENGG SFSIHIEQNP RYSINAIHIE NITICRQERG
RGGLLIDLTS YKSVFVGSSL FFANTVPSAT IILKYNQDDV DKSNAKTPSF MLTGNRFDSN
NNFVVHARME SSVITRIHNN NFVGNNERSK SGTAIVEIAP DEHSKQFQVE ISNNLWANNK
GAWCLYIIAN NQNPFNGSVH GNKFERNENI RGSLIVGSSF FRINENEFNN HLEKFDLEVD
FLQNDLLDAA NNYWGYEDDE SIEKRVLDGR TDHSRGIAKI RPINLKRAAA IPDDCVAVSN
CSMNGQCIGH NQCLCESGFA GEDCSRISCL SLNNCSTNGY CVAPNLCQCN DGWLEIDCSR
PSCELVANCS GHGECVSLNE CLCDPMYQGA SCSEPTTNCS ITGCNNHGSC VSGECICESG
WTAPFCSRAV CDRTNNCSNS GTCVKPNLCE CAPGYSGDDC SVCEGSACSQ CEFRCVHGAC
DPNSRVCVCR GDWIGAACDI CARDKCDALS VALFILPPAV GVHREDGTVV TVYGNDFPTA
QSDRYICLYG STATSGRYIT STRIQCEIPH SMLPGRYLFN VIPYGSERAL PFVDKRTTHF
TFYIECDPSR CAGFCIGPTC VCPLDRTGIL CEQTKFPPNI DREIINNDKL TKAIEGQPYN
IKIPLQQRNV IFNLQSDAEG MHVTSNGIVT WTQPIGRGQP YKINLTLDSQ AGESMISWNL
TVIPTYSPII TRITNVGETN KRAIQGIVQF IDQKSFGQVP VRLQIFRNKI LSEDVTVKSD
KSGRFEYIHI PSDEASSYMA MAIHPGEAVY NSSNDAYRFA SWSDVGFEVD YDQLLEVTPG
ASSNTVYHLR NNGDVPLAAC WIQIITPRDK IYIDKVEQGF ESIGVNESKD MRVMFAISST
LDNVIATLQF SCVNSVKRLI RQSFVIEGTR PRLRPYPSEL LLSFAPQTLA PIIEIDLINE
GIDLKAPLSI IVSPNNSPVF VAATNPVLSD FREYNMNGTT ISLFLGLRSP MNYTLNESLP
GNISIAYHNE SVLSIPYRFV VGSTFFNFFV TIRDELTAVD ASAKVPGALV HLRNNAIGFD
DQRQTRGDEA TVFFSITEGA YELTVSSPIH QTVSMIVQAS SANSSLTVFL PIAFPFVPML
DEDELVLEEF DKQTAVPLPV LRLTPPSLRI PKADSMNYSF VAENIGGSPE SSVALPPIIF
DEHSLPFRLL MNGIRNGIGL NDGYRTSIEL TRLNDGDDSE RCNVYALRIP YYYTIPRSFS
NYMRHALMLI DNRDISKQSG KDVNICEAGA DRTLQQSAIW TKTAIQCNCA MNARERCRKQ
YVSATLCGSA WKFIPDDTVS LDSIAMFVLL ISNCNAVGVN FDKLQKSIAC ASALDSRCPM
LRRRRSASNF RTIRNDSIRL NDRPTQFFAH LAAVSEQVDG ILQQYFPAFN ALEIQAVNMA
SLYFDFFEQL QVVLPSQYFT GITSRQWFDD FFRAIADSSD GGRLITTVEL NGFRDKDVSE
RFIKVWNATV VLWTSGQIDP LVEQNGPGIS FADVRKLIVR SDRLKSLSRQ YGADNPFALL
HDHIGRLLSV DNTPPPYPFS SANDNEDICA IGYTLISPSK PSENDEIVVK LRIDNKKRGP
LLNIRVSLEM LRERPDTTPI QFRIGPLTFE GIRSLDGDAH LPANSSFTAQ WLIRPVHSSR
LMNIARYQAI VIVKFFVDDR PNVQRIETRS VPIQPRPSLK IYYFISPKMN FT
//
