ID F1KUG1_ASCSU Unreviewed; 667 AA.
AC F1KUG1;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=ATP-binding cassette sub-family F member 1 {ECO:0000313|EMBL:ADY41515.1};
OS Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6253 {ECO:0000313|EMBL:ADY41515.1};
RN [1] {ECO:0000313|EMBL:ADY41515.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21685128; DOI=10.1101/gr.121426.111;
RA Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA Davis R.E.;
RT "Deep small RNA sequencing from the nematode Ascaris reveals conservation,
RT functional diversification, and novel developmental profiles.";
RL Genome Res. 21:1462-1477(2011).
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCF family.
CC EF3 subfamily. {ECO:0000256|ARBA:ARBA00011054}.
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DR EMBL; JI166062; ADY41515.1; -; mRNA.
DR AlphaFoldDB; F1KUG1; -.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03221; ABCF_EF-3; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR032781; ABC_tran_Xtn.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19211:SF14; ATP-BINDING CASSETTE SUB-FAMILY F MEMBER 3; 1.
DR PANTHER; PTHR19211; ATP-BINDING TRANSPORT PROTEIN-RELATED; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF12848; ABC_tran_Xtn; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 2: Evidence at transcript level;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:ADY41515.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 122..366
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 449..662
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 380..421
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..399
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 74458 MW; 36DD4862E280867E CRC64;
MLSADTISVP NVCALNLSCL YRQLVRRTMS DTEVAGTMAS LKVNGKDKKL SRKELKKLQK
KAEYEREVLA MGGQVDGKSD ENVEKKEGGG IGSGVELGNQ FSVSQQAKSA AQLAQLENAV
DIKVENFDIT AQGRTLFHKA DLTIAFGRRY GLVGPNGMGK TTLLKHIAGR KLAIPPNIDL
LYCEQEIEVD KTSAIDTVVK SDKRRLELIK EEAELTKKLE SGDMNAGERL KEVTEELRDI
GADAAEPKAR RILAGLGFSK AMQEKPVEAF SGGWRMRISL ARALFLEPTL LMLDEPTNHL
DLNAVIWLDN YLQSWKKTLL IVSHDQGFLD NVCTDIIDLL DQKLYYYKGN YSSFKKMRDQ
KLREHMKAYE TQQKQITALK KSGKSAKQAA EEMKSRLQNK QNKAGKAKKG SSAIGDEEAE
PPPELLQRIK EYSVKFVFPD PPKLPPPVLG LHNVSFGYKD QVLFKNLDFG VDMDSRIAIV
GPNGVGKSTL LKLLYGKIEP QQGEMRKHRQ LRIGWFDQHA NEALNQEQTP IEYLGLKFQI
DYQEARKRLG TVGLPGHSHT VKIKDLSGGQ KSRVALAELA LSAPDILILD EPTNNLDIES
IHALAEAIEE FGGGVVMVTH DERLIRETNC QLWIVEDYNV AEIDGDFDDY RKEILDQLGE
TLAVPQS
//
