ID   F1L1S6_ASCSU            Unreviewed;       634 AA.
AC   F1L1S6;
DT   03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT   03-MAY-2011, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Protein lap1 {ECO:0000313|EMBL:ADY44080.1};
DE   Flags: Fragment;
OS   Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6253 {ECO:0000313|EMBL:ADY44080.1};
RN   [1] {ECO:0000313|EMBL:ADY44080.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=21685128; DOI=10.1101/gr.121426.111;
RA   Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA   Davis R.E.;
RT   "Deep small RNA sequencing from the nematode Ascaris reveals conservation,
RT   functional diversification, and novel developmental profiles.";
RL   Genome Res. 21:1462-1477(2011).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC       {ECO:0000256|ARBA:ARBA00004170}.
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DR   EMBL; JI169745; ADY44080.1; -; mRNA.
DR   AlphaFoldDB; F1L1S6; -.
DR   Gene3D; 2.30.42.10; -; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR036034; PDZ_sf.
DR   PANTHER; PTHR23119; DISCS LARGE; 1.
DR   PANTHER; PTHR23119:SF44; PROTEIN SCRIBBLE HOMOLOG; 1.
DR   Pfam; PF00560; LRR_1; 1.
DR   Pfam; PF13855; LRR_8; 4.
DR   SMART; SM00364; LRR_BAC; 11.
DR   SMART; SM00369; LRR_TYP; 12.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   PROSITE; PS51450; LRR; 2.
PE   2: Evidence at transcript level;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REGION          445..538
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        446..467
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..525
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         634
FT                   /evidence="ECO:0000313|EMBL:ADY44080.1"
SQ   SEQUENCE   634 AA;  70420 MW;  172137FE0D1F5003 CRC64;
     MPIFSCVPFT CSGRVDVIEK RQCNLHELPA EVERSASCLE ELYLDCNQIC EIPEGLCRCK
     KLRSLSLGQN KILRVPPAIG SLIALEELHL EDNELSDLPE ELVKCSNLKI LDLRLNLLTR
     LPDVVTRLSS LTHLYLFETS LTQLPPDIDQ LQNLRSLDVR ENQLRILPPA ICQLKHLREL
     DLGRNELSHL PLNMGSLEVL EDLYVDHNVL SAVPDSLTSC GHLRTLDVSQ NDLTALPKEI
     GDLEQLCELS IAENRIAALP NSIGRLKNLV TLKADSNALT ELVPTIGECS SLLELYLFNN
     QLTTLPATIG GLKELSVLSI DENQLEEIPS AIGGCSKLSI LTLRGNRLRE LPLEVGRLAN
     LRVLDLCDNI LAFLPFTINV LFNLRALWLS VDQTSPLVPF ESAQDPVTRV KVLTTYLLPQ
     GKCQEEAGLM HPRRVSAGVS VRFGSEEGAS DEDESVGHFE RKGTPHPKTR SRAVTPRRQS
     IDGHFIPHSD SNDNSDSTLS LRRKSAGDVP NSDGSIFQRS SQIESENSEY RSKAHHSEAE
     EVNGVKMPKS IMRNVSSTSR CHITIVRDAI SGFGLSLAGG RDSEPFKVND TGLFISRVVD
     RRTFRSSRIA CRRQNTFCER RLSCRRASSC GLPK
//