ID F1L467_ASCSU Unreviewed; 474 AA.
AC F1L467;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Ski oncogene {ECO:0000313|EMBL:ADY44921.1};
OS Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6253 {ECO:0000313|EMBL:ADY44921.1};
RN [1] {ECO:0000313|EMBL:ADY44921.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21685128; DOI=10.1101/gr.121426.111;
RA Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA Davis R.E.;
RT "Deep small RNA sequencing from the nematode Ascaris reveals conservation,
RT functional diversification, and novel developmental profiles.";
RL Genome Res. 21:1462-1477(2011).
CC -!- SIMILARITY: Belongs to the SKI family. {ECO:0000256|ARBA:ARBA00009513}.
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DR EMBL; JI171008; ADY44921.1; -; mRNA.
DR AlphaFoldDB; F1L467; -.
DR EnsemblMetazoa; AgR011_g042_t01; AgR011_g042_t01; AgR011_g042.
DR EnsemblMetazoa; AgR011_g042_t02; AgR011_g042_t02; AgR011_g042.
DR GO; GO:0046332; F:SMAD binding; IEA:InterPro.
DR CDD; cd21079; DHD_Ski_Sno; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR Gene3D; 3.10.260.20; Ski; 1.
DR InterPro; IPR014890; c-SKI_SMAD4-bd_dom.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR003380; SKI/SNO/DAC.
DR InterPro; IPR037000; Ski_DNA-bd_sf.
DR InterPro; IPR023216; Tscrpt_reg_SKI_SnoN.
DR PANTHER; PTHR10005; SKI ONCOGENE-RELATED; 1.
DR PANTHER; PTHR10005:SF25; SNO ONCOGENE, ISOFORM B; 1.
DR Pfam; PF08782; c-SKI_SMAD_bind; 1.
DR Pfam; PF02437; Ski_Sno; 1.
DR SMART; SM01046; c-SKI_SMAD_bind; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR SUPFAM; SSF63763; SAND domain-like; 1.
PE 2: Evidence at transcript level;
FT DOMAIN 156..246
FT /note="c-SKI SMAD4-binding"
FT /evidence="ECO:0000259|SMART:SM01046"
SQ SEQUENCE 474 AA; 51375 MW; F518D5109E2729AC CRC64;
MALTAMRRDI HSMCHGEDIL LEELSSRLKG VLPVQPSPLL VPSDSTSSSL KSTMLGGHLI
SCFVIGGECR LCFPQIISVV LQGVKVDDVN DLFVDLNIHI SVASQQQLDT LKLAGVMPMT
ADSCGLVTKS DAERLVAKLL PQTNGPLRGV VSRDDAVPIC HDCFGGCKGT LLPSLHCEEC
IECDECKYMF SGEKFVAHTH SLKEIRRVCH WGFDSANWKY YLRIAETHED DIRAVQRLEH
FKNPHIRIGK RHNECKLSDS DGLPTKAMGI EPCSLLELGQ LMSSRTMVPL SSASLLGAQM
YSMSPQLQSL IALQLAAAAT QLPLAAASAQ PNAANCAKVA TETKQQQAGG GGSFCGGADR
LVKPVPVKSD LCIVDESNRL SKKISPSSEL GLNGTVNPNT ALSLEKLLEE NMKEPALSLA
KIMLAESGRA EARKREELSA QVEQLRRENC ILRGALSRNA LLISQSLPQK TNIC
//
