ID F1L5D9_ASCSU Unreviewed; 430 AA.
AC F1L5D9;
DT 03-MAY-2011, integrated into UniProtKB/TrEMBL.
DT 03-MAY-2011, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Transient-receptor-potential-like protein {ECO:0000313|EMBL:ADY45343.1};
OS Ascaris suum (Pig roundworm) (Ascaris lumbricoides).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX NCBI_TaxID=6253 {ECO:0000313|EMBL:ADY45343.1};
RN [1] {ECO:0000313|EMBL:ADY45343.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=21685128; DOI=10.1101/gr.121426.111;
RA Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J.,
RA Davis R.E.;
RT "Deep small RNA sequencing from the nematode Ascaris reveals conservation,
RT functional diversification, and novel developmental profiles.";
RL Genome Res. 21:1462-1477(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JI171690; ADY45343.1; -; mRNA.
DR AlphaFoldDB; F1L5D9; -.
DR EnsemblMetazoa; AgB26_g026_t02; AgB26_g026_t02; AgB26_g026.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005262; F:calcium channel activity; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR013555; TRP_dom.
DR InterPro; IPR002153; TRPC_channel.
DR PANTHER; PTHR10117; TRANSIENT RECEPTOR POTENTIAL CHANNEL; 1.
DR PANTHER; PTHR10117:SF47; TRANSIENT-RECEPTOR-POTENTIAL-LIKE PROTEIN; 1.
DR Pfam; PF08344; TRP_2; 1.
DR SMART; SM01420; TRP_2; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
PE 2: Evidence at transcript level;
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:ADY45343.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 359..376
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 171..231
FT /note="Transient receptor ion channel"
FT /evidence="ECO:0000259|SMART:SM01420"
SQ SEQUENCE 430 AA; 49193 MW; E63D4B7FDB95D73B CRC64;
MAAKGGHGAS LLRETLLPYK FPSEVGKDSG FDGIIKWKRS EQSAMLIRHF RHAVLKKDLD
TVKSTIAALK PDMHEDEVDR LSSLLLDRSS AEPTKEALMT AICIGSRPLV EFILSLFYEF
PQEERNGCKN SIAYPSHITP LMLAAICNNF AIVQCLLLRN HHICLPHRPD CLCSECRRIA
RGLSKSVVTL DTYRAISSAA FLWLACSDPS LAAFRLAADL EICMQYEQEY RMIYQQLHRN
VMAFGVRLVQ QCWNMEEVDL LLSRMDGAPL SYYEMRLPRL RVALDCRVKN LLSTLNAQTA
VHAEWCGEWT DYGSDVVLDT WRHVKHAFLY PIAASIHTFT AGCYVRSFNY PVARYISEMA
SYVLFLIILL VIRLSGRKGD RAVERSVKEN PKEYILEGYV YLYAIGMALR HYISLCNRGM
SAFYDVWWTW
//
